General Information:

Id: 948
Diseases: Alzheimer disease - [OMIM]
Mus musculus
Three- to four-month-old female transgenic mice overexpressing the human APP gene containing the Swedish mutation that causes familial AD (Tg2576 mouse model)
article
Reference: Chen F et al.(2006) Reductions in levels of the Alzheimers amyloid beta peptide after oral administration of ginsenosides FASEB J. 20: 1269-1271 [PMID: 16636099]

Interaction Information:

Comment Oral administration of ginsenoside RE, Rg1, or Rg3 results in significant reductions in Abeta levels in the brains of Tg2576 mice, a mouse model of Abeta accumulation.
Formal Description
Interaction-ID: 5757

drug/chemical compound

Ginsenoside Re

decreases_quantity of

in brain
Comment Oral administration of ginsenoside RE, Rg1, or Rg3 results in significant reductions in Abeta levels in the brains of Tg2576 mice, a mouse model of Abeta accumulation.
Formal Description
Interaction-ID: 5760

drug/chemical compound

Ginsenoside Rg1

decreases_quantity of

in brain
Comment Oral administration of ginsenoside RE, Rg1, or Rg3 results in significant reductions in Abeta levels in the brains of Tg2576 mice, a mouse model of Abeta accumulation.
Formal Description
Interaction-ID: 5761

drug/chemical compound

Ginsenoside Rg3

decreases_quantity of

in brain
Comment Oral administration of ginsenoside RE, Rg1, or Rg3 results in significant reductions in Abeta levels in the brains of Tg2576 mice, a mouse model of Abeta accumulation.
Formal Description
Interaction-ID: 5833

drug/chemical compound

Ginsenoside Re

decreases_quantity of

in brain
Comment Oral administration of ginsenoside RE, Rg1, or Rg3 results in significant reductions in Abeta levels in the brains of Tg2576 mice, a mouse model of Abeta accumulation.
Formal Description
Interaction-ID: 5834

drug/chemical compound

Ginsenoside Rg1

decreases_quantity of

in brain
Comment Oral administration of ginsenoside RE, Rg1, or Rg3 results in significant reductions in Abeta levels in the brains of Tg2576 mice, a mouse model of Abeta accumulation.
Formal Description
Interaction-ID: 5835

drug/chemical compound

Ginsenoside Rg3

decreases_quantity of

in brain