General Information:

Id: 758
Diseases: Neurological
Homo sapiens
BTO:0000942 NG-108-15 cell
article
Reference: Gramage E et al.(2008) Pleiotrophin prevents cocaine-induced toxicity in vitro. Eur. J. Pharmacol. 595: 35-38 [PMID: 18727926]

Interaction Information:

Comment Pleiotrophin is a cytokine involved in differentiation, survival and repair processes in the central nervous system.
Formal Description
Interaction-ID: 4272

gene/protein

PTN

affects_activity of

in the central nervous system
Comment Pleiotrophin is a cytokine involved in differentiation, survival and repair processes in the central nervous system.
Formal Description
Interaction-ID: 4274

gene/protein

PTN

affects_activity of

Comment Pleiotrophin significantly prevents cocaine-induced cytotoxicity.
Formal Description
Interaction-ID: 4276

drug/chemical compound

Cocaine

increases_activity of

process

neuron death

Drugbank entries Show/Hide entries for Cocaine
Comment Pleiotrophin significantly prevents cocaine-induced cytotoxicity.
Formal Description
Interaction-ID: 4278

gene/protein

PTN

decreases_activity of

drug/chemical compound

Cocaine

Drugbank entries Show/Hide entries for
Comment Pleiotrophin significantly prevents cocaine-induced cytotoxicity.
Formal Description
Interaction-ID: 4281

gene/protein

PTN

decreases_activity of

process

neuron death