General Information:

Id: 6,300 (click here to show other Interactions for entry)
Diseases: Prostate cancer - [OMIM]
Homo sapiens
article
Reference: Ummanni R et al.(2008) Prohibitin identified by proteomic analysis of prostate biopsies distinguishes hyperplasia and cancer Cancer Lett. 266: 171-185 [PMID: 18384941]

Interaction Information:

Comment The present study investigated biopsy samples from benign prostate hyperplasia (BPH, n=11) and prostate cancer (PCA, n=12) patients. by two-dimensional gel electrophoresis (2-DE) and mass spectrometry to identify potential biomarkers which might distinguish the two clinical situations. 2-DE results revealed 88 protein spots expressed differentially among hyperplasia and cancer groups with statistical significance. Interesting spots were analyzed by MALDI-TOF-MS-MS and 79 different proteins were identified.
Formal Description
Interaction-ID: 59210

disease

Prostate cancer

increases_expression of

gene/protein

SERPINC1

in cancer cells
Drugbank entries Show/Hide entries for SERPINC1