General Information:

Id: 5,632
Diseases: Cardiomyopathy, hypertrophic
Mus musculus
article
Reference: Lu H et al.(2006) Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice Circulation 114: 2271-2279 [PMID: 17088456]

Interaction Information:

Comment The increase in ILK was associated with activation of the Rho family guanine triphosphatases, Rac1 and Cdc42, and known hypertrophic signaling kinases, including extracellular signal-related kinases (ERK1/2) and p70 S6 kinase.
Formal Description
Interaction-ID: 53845

gene/protein

ILK

increases_activity of

gene/protein

CDC42

Drugbank entries Show/Hide entries for CDC42