General Information:

Id: 520 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
BTO:0000793 SHSY-5Y cell (neuroblastoma cells)
article
Reference: Beher D et al.(2003) In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand Biochemistry 42: 8133-8142 [PMID: 12846562]

Interaction Information:

Comment Gamma-secretase activities generating amyloid-beta(40) peptides and amyloid-beta(42) are both carried out by the same molecular entity.
Formal Description
Interaction-ID: 2586

complex/PPI

Gamma-secretase complex

increases_quantity of