General Information:

Id: 3,622 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Hyperthyroidism
Hypothyroidism
Insulin resistance
Mammalia
review
Reference: Brenta G(2011) Why can insulin resistance be a natural consequence of thyroid dysfunction? J Thyroid Res 2011 [PMID: 21941681]

Interaction Information:

Comment In skeletal muscle, the main site of insulin-mediated glucose disposal, glucose transporter GLUT4, is induced by T3, revealing that it can increase basal and insulin-stimulated glucose transport in this tissue.
Formal Description
Interaction-ID: 34308

drug/chemical compound

Triiodothyronine

increases_expression of

gene/protein

SLC2A4

in skeletal muscle
Comment In skeletal muscle, the main site of insulin-mediated glucose disposal, glucose transporter GLUT4, is induced by T3, revealing that it can increase basal and insulin-stimulated glucose transport in this tissue.
Formal Description
Interaction-ID: 34310

gene/protein

SLC2A4

increases_activity of

process

glucose import

in skeletal muscle