General Information:

Id: 3,284 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Metabolic syndrome
Homo sapiens
article
Reference: Graham TE et al.(2006) Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects N. Engl. J. Med. 354: 2552-2563 [PMID: 16775236]

Interaction Information:

Comment GLUT4 mRNA and protein are reduced in adipocytes in many insulin-resistant states, often long before type 2 diabetes develops. Adipocyte GLUT4 protein and serum RBP4 levels were inversely correlated.
Formal Description
Interaction-ID: 30221

phenotype

increased circulating RBP4 level

decreases_quantity of

gene/protein

SLC2A4

in adipose tissue