General Information:

Id: 2,911
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
article
Reference: Dunn SE et al.(1997) Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice. Cancer Res. 57: 4667-4672 [PMID: 9354418]

Interaction Information:

Comment Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice.
Formal Description
Interaction-ID: 26682

environment

calorie restriction

decreases_activity of

Comment Dietary restriction lowered IGF-I levels, thereby favoring apoptosis over cell proliferation and ultimately slowing tumor progression.
Formal Description
Interaction-ID: 26688
Comment Dietary restriction lowered IGF-I levels, thereby favoring apoptosis over cell proliferation and ultimately slowing tumor progression.
Formal Description
Interaction-ID: 26689