General Information:

Id: 2,416 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
Reference: Boesgaard TW et al.(2010) Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people Diabetologia 53: 1647-1655 [PMID: 20419449]

Interaction Information:

Comment Carriers of the glucose-raising A-allele of GLIS3 rs7034200 had a decreased glucose-stimulated insulin release.
Formal Description
Interaction-ID: 21745

decreases_activity of

the effective allele is A