General Information:

Id: 2,311 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
BTO:0000156 brown adipose tissue
Reference: Hernandez R et al.(2003) Rosiglitazone produces insulin sensitisation by increasing expression of the insulin receptor and its tyrosine kinase activity in brown adipocytes. Diabetologia 46: 1618-1628 [PMID: 14595539]

Interaction Information:

Comment Rosiglitazone also produced a 40% increase in insulin-stimulated glucose uptake as a result of increased GLUT4 translocation to the plasma membrane. This happened without changes in the expression of GLUT4 at the mRNA or protein level.
Formal Description
Interaction-ID: 19857

drug/chemical compound


NOT affects_quantity of



in brown adipose tissue
Drugbank entries Show/Hide entries for Rosiglitazone