General Information:

Id: 1,990 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article
Reference: Miyata T et al.(1998) Bradykinin potentiates insulin-stimulated glucose uptake and enhances insulin signal through the bradykinin B2 receptor in dog skeletal muscle and rat L6 myoblasts. Eur. J. Endocrinol. 138: 344-352 [PMID: 9539311]

Interaction Information:

Comment Bradykinin enhanced insulin-stimulated GLUT4 translocation, and insulin-induced phosphorylation of insulin receptor beta subunit and insulin receptor substrate-1 (IRS-1) without affecting the binding affinities or numbers of cell surface insulin receptors in isolated dog skeletal muscle and rat L6 myoblasts.
Formal Description
Interaction-ID: 15700

gene/protein

Bradykinin

increases_transport of

gene/protein

SLC2A4

in skeletal muscle; to the plasma membrane; if induced by insulin