General Information:

Id: 1,519 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Obesity - [OMIM]
Mus musculus
male
ob/ob mouse
article
Reference: Gonzalez-Periz A et al.(2009) Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins FASEB J. 23: 1946-1957 [PMID: 19211925]

Interaction Information:

Comment Increased adiponectin expression in mice fed omega-3-PUFAs was associated with up-regulation in the adipose tissue of insulin-sensitizing genes (i.e., PPAR-gamma) and genes coding for insulin receptor signaling (i.e., IRS-1, the substrate protein for the insulin receptor) as well as glucose transport (i.e., GLUT-4, the glucose transporter).
Formal Description
Interaction-ID: 10780

drug/chemical compound

Polyunsaturated fatty acid, omega-3

increases_expression of

gene/protein

SLC2A4

in adipose tissue