General Information:

Id: 1,450 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
male
article
Reference: Franckhauser S et al.(2008) Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice Diabetologia 51: 1306-1316 [PMID: 18437347]

Interaction Information:

Comment High levels of circulating IL-6 lead to decreased skeletal muscle glucose uptake and GLUT-4 content.
Formal Description
Interaction-ID: 10214

gene/protein

IL6

decreases_quantity of

gene/protein

SLC2A4

in skeletal muscle; if IL6 is overexpressed in skeletal muscle
Drugbank entries Show/Hide entries for IL6