General Information:

Id: 1,445 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
BTO:0000011 3T3-L1 cell
article
Reference: Jager J et al.(2007) Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression Endocrinology 148: 241-251 [PMID: 17038556]

Interaction Information:

Comment In 3T3-L1 adipocytes IL-1beta treatment increased the amount of Glut 1 and slightly decreased Glut 4 expression but did not modify the differentiation state of adipocyte because C/EBP-alpha, PPAR-gamma, and adipocyte lipid binding protein 2 mRNAs expression was not altered.
Formal Description
Interaction-ID: 10162

gene/protein

IL1B

decreases_quantity of

gene/protein

SLC2A4

Drugbank entries Show/Hide entries for IL1B