General Information:

Id: 13,354
Diseases: COVID-19
Homo sapiens
Reference: Zhang L et al.(2020) D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19 J Thromb Haemost 18: 1324-1329 [PMID: 32306492]

Interaction Information:

Comment A total of 343 eligible patients were enrolled in the study. The optimum cutoff value of D-dimer to predict in-hospital mortality was 2.0 µg/mL with a sensitivity of 92.3% and a specificity of 83.3%. There were 67 patients with D-dimer >2.0 µg/mL, and 267 patients with D-dimer <2.0 µg/mL on admission. 13 deaths occurred during hospitalization. Patients with D-dimer levels >2.0 µg/mL had a higher incidence of mortality when comparing with those who with D-dimer levels <2.0 µg/mL.
Formal Description
Interaction-ID: 125998


SARS-CoV-2 infection

increases_quantity of



Comment D-dimer on admission greater than 2.0 µg/mL (fourfold increase) could effectively predict in-hospital mortality in patients with Covid-19, which indicated D-dimer could be an early and helpful marker to improve management of Covid-19 patients.
Formal Description
Interaction-ID: 125999



affects_activity of