General Information:

Id: 11,754 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Randriamboavonjy V et al.(2012) Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes Blood 120: 415-423 [PMID: 22665935]

Interaction Information:

Comment Levels of septin-5 and ILK were reduced in diabetic versus healthy subjects and increased as a result of pioglitazone therapy, which also reduced mu- and m-calpain activation.
Formal Description
Interaction-ID: 116507

decreases_expression of

gene/protein

ILK

Comment Levels of septin-5 and ILK were reduced in diabetic versus healthy subjects and increased as a result of pioglitazone therapy, which also reduced mu- and m-calpain activation.
Formal Description
Interaction-ID: 116509

drug/chemical compound

Pioglitazone

increases_expression of

gene/protein

ILK

in diabetic patients
Drugbank entries Show/Hide entries for Pioglitazone