Search Results for "TSC2" - 30 interactions found in 14 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
2,845
26219 Metformin affects_activity of TSC2
18006825 Diabetes mellitus, type II
Cancer
Insulin resistance
2,863
26416 TSC2 affects_activity of insulin secretion in pancreas, in pancreatic islets
26417 TSC2 affects_activity of mTORC1 complex
26423 TSC2 affects_activity of increased circulating insulin level
21886784 Diabetes mellitus, type II
Insulin resistance
3,795
37686 AMPK increases_phosphorylation of TSC2 in collaboration with GSK3
18765678 Diabetes mellitus, type II
Insulin resistance
4,409
44925 TSC2 decreases_activity of MTOR
44926 TSC2 is_part_of Beta-catenin destruction complex
44928 GSK3B increases_activity of TSC2
22131415 Metabolic
5,364
52363 TSC1 interacts (colocalizes) with TSC2
52370 TSC2 is_part_of TSC1-TSC2 complex
21134130 Metabolic
6,387
61023 GSK3B increases_phosphorylation of TSC2 therefore acting as negative regulator of mTORC1.
61028 TSC2 is_part_of TSC1-TSC2 complex
61670 AMPK increases_phosphorylation of TSC2
25955819 Metabolic
6,456
61368 AMPK increases_activity of TSC2 via phosphorylation at Ser1345
61369 TSC2 decreases_activity of RHEB via increased RHEB-GDP binding
22117616 Diabetes mellitus, type II
Cancer
Insulin resistance
6,900
68061 CCN4 affects_activity of TSC2
27127460 Diabetes mellitus, type II
Insulin resistance
7,046
69297 TSC2 affects_activity of mitochondrial depolarization in pancreatic beta cells
69349 TSC2 affects_activity of response to endoplasmic reticulum stress
26900135 Diabetes mellitus, type II
Obesity
Insulin resistance
7,420
72932 protein kinase B signaling decreases_activity of TSC2
26862218 Diabetes mellitus, type II
Insulin resistance
8,307
84221 TSC1 interacts (colocalizes) with TSC2
84222 energy homeostasis affects_activity of TSC2
84223 AMPK increases_phosphorylation of TSC2 under energy starvation condition
84225 TSC2 is_part_of TSC1-TSC2 complex
84230 AMPK increases_activity of TSC2 under energy starvation condition
84232 TSC2 affects_activity of regulation of translation under energy starvation condition via phosphorylation of TSC2
84234 TSC2 affects_activity of regulation of cell size under energy starvation condition via phosphorylation of TSC2
14651849 Metabolic
8,492
86963 TSC2 is_part_of TSC (TSC1, TSC2, AXIN, GSK3) complex
86966 TSC1 interacts (colocalizes) with TSC2
15972957 Metabolic
10,691
109356 CIAO1 interacts (colocalizes) with TSC2
23891004 Metabolic
11,544
115385 RPS6KA1 increases_phosphorylation of TSC2
30813401 Cardiovascular disease
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