Search Results for "SNCA" - 245 interactions found in 83 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
8
21 LRRK2 NOT interacts (colocalizes) with SNCA
16352719 Parkinson disease
40
92 SNCA interacts (colocalizes) with MAPT in axons of hippocampal neurons
94 SNCA increases_phosphorylation of MAPT by protein kinase A
98 SNCA is localized in axon of hippocampal neurons
10464279 Parkinson disease
44
114 SNCA increases_quantity of tau protein deposits
118 SNCA increases_folding of MAPT
119 MAPT increases_folding of SNCA
12714745 Parkinson disease
Tauopathy
Synucleinopathy
52
138 mir-7 decreases_expression of SNCA
19628698 Parkinson disease
55
156 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases_expression of SNCA
19628698 Parkinson disease
61
188 MAPT interacts (colocalizes) with SNCA in Lewy bodies
12722831 Alzheimer disease
Parkinson disease
Diffuse Lewy Body disease
125
431 SNCA is localized in mitochondrion if SNCA is overexpressed
435 SNCA increases_quantity of CYCS in the cytoplasm; if SNCA is overexpressed
440 SNCA increases_quantity of NO in mitochondria; if SNCA is overexpressed
449 SNCA increases_quantity of Ca2+ in mitochondria; if SNCA is overexpressed
13588 SNCA increases_activity of release of cytochrome c from mitochondria if SNCA is overexpressed
18322646 Parkinson disease
142
511 SNCA is localized in aggresome if SNCA is overexpressed
16805805 Parkinson disease
215
910 SNCA increases_quantity of MEF2D by inhibiting CMA-mediated degradation of MEF2D
912 SNCA decreases_quantity of MEF2D-HSC70 complex if SNCA is overexpressed
914 SNCA decreases transport of MEF2D into lysosomes; if SNCA is overexpressed
19119233 Parkinson disease
222
994 AMFR NOT decreases_quantity of SNCA
19661182 Amyotrophic lateral sclerosis
224
918 SNCA NOT increases_quantity of MEF2D in cortex
19119233 Parkinson disease
225
922 Parkinson disease increases_quantity of SNCA in brain
19119233 Parkinson disease
227
923 autophagy decreases_quantity of SNCA
18566453 Parkinson disease
228
10397 autophagy decreases_quantity of SNCA
18566453 Parkinson disease
229
925 SNCA interacts (colocalizes) with LAMP2
18566453 Parkinson disease
241
999 SNCA interacts (colocalizes) with LAMP2
18566453 Parkinson disease
366
1473 LRRK2 increases_phosphorylation of SNCA at amino acid position 129
1475 LRRK2-p.G2019S increases_phosphorylation of SNCA at amino acid position 129; with a significantly higher rate than WT LRRK2
1956 SNCA is localized in alpha-synuclein inclusion body if SNCA is phosphorylated
19576176 Parkinson disease
408
1772 SNCA interacts (colocalizes) with TUBA
1773 SNCA interacts (colocalizes) with TUBB
1774 SNCA interacts (colocalizes) with Alpha/beta-tubulin complex
1961 SNCA is localized in alpha-synuclein inclusion body
11698390 Parkinson disease
409
1780 SNCA is localized in microtubule
1784 Alpha/beta-tubulin complex increases_folding of SNCA
11698390 Parkinson disease
477
2236 Ammonium chloride increases_quantity of SNCA by inhibiting lysosomal degradation (autophagy)
2240 Epoxomicin NOT increases_quantity of SNCA by inhibiting proteasomal degradation
15333840 Parkinson disease
479
2244 response to starvation decreases_quantity of SNCA
2248 Ammonium chloride increases_quantity of SNCA irrespective of serum is added or not
2256 SNCA is localized in lysosome
2257 autophagy decreases_quantity of SNCA
2262 SNCA interacts (colocalizes) with lysosome
2263 SNCA interacts (colocalizes) with LAMP2
15333840 Parkinson disease
482
2288 Dopamine increases_expression of SNCA
12868068 Parkinson disease
504
2474 SNCA increases_quantity of inclusion body
2493 SNCA increases_quantity of alpha-synuclein inclusion body
2499 SNCA decreases_activity of autophagy if SNCA is overexpressed
2503 SNCA decreases_activity of neuron projection development if SNCA is overexpressed
19864570 Dementia, Lewy body
Parkinson disease
558
3006 SNCA is localized in alpha-synuclein inclusion body
12000718 Dementia, Lewy body
Parkinson disease 2, autosomal recessive juvenile
Parkinson disease
662
3548 SNCA affects_activity of Parkinson disease
19915575 Parkinson disease
Tauopathy
695
3844 SNCA interacts (colocalizes) with TUBB3
20064389 Parkinson disease
750
4228 SOD1-p.G93A NOT interacts (colocalizes) with SNCA
19478559 Alzheimer disease
Amyotrophic lateral sclerosis
791
4482 STUB1 decreases_quantity of SNCA by degradation of SNCA via the proteasomal and the lysosomal degradation pathways
15845543 Parkinson disease
797
4589 Geldanamycin decreases_quantity of SNCA if cells were treated with GA prior to transfection with SNCA.
4590 SNCA increases_activity of neuron death if SNCA is overexpressed
15358157 Parkinson disease
818
4742 SNCA interacts (colocalizes) with PLD1
4743 SNCA decreases_activity of PLD1
4744 SNCA interacts (colocalizes) with PRKCA
4745 SNCA interacts (colocalizes) with PLD2
4746 SNCA NOT interacts (colocalizes) with PLCB1
11821392 Parkinson disease
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