Search Results for "PPARA" - 206 interactions found in 65 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
386
1719 Mitochondrial GPAT NOT affects_expression of PPARA if mitochondrial GPAT is overexpressed in liver
16507761 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
598
3201 high-phytoestrogen soy-based diet increases_expression of PPARA
18420492 Diabetes mellitus, type II
Obesity
Insulin resistance
664
3710 LEP increases_expression of PPARA in adipose tissue; in lean ZDF rats
10940327 Diabetes mellitus, type II
Diabetes mellitus, type I
Insulin resistance
Hypothyroidism
714
3995 PPARA increases_expression of MTTP in liver
3996 Fibric acid derivative increases_activity of PPARA
18927507 Diabetes mellitus, type II
Abetalipoproteinemia
Insulin resistance
Fatty liver disease, nonalcoholic
Cardiovascular disease
732
4113 dietary fat affects_activity of PPARA in liver
16614395 Diabetes mellitus, type II
Insulin resistance
787
4410 LPIN1 increases_expression of PPARA
4493 LPIN1 interacts (colocalizes) with PPARA
16950137 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
824
4766 PPARA interacts (colocalizes) with RXR upon ligand binding
4773 PPARA affects_expression of CPT1A
4777 PPARA affects_expression of ACADM
4778 PPARA affects_expression of HMGCS2 in liver
4780 PPARA affects_expression of ACOX in liver
4783 PPARA affects_activity of fatty-acyl group transport into mitochondria
4784 PPARA affects_activity of fatty acid beta-oxidation
4785 PPARA affects_activity of ketone body biosynthetic process in liver
4786 PPARA affects_activity of lipid homeostasis
4787 PPARA decreases_activity of Insulin resistance in liver, in skeletal muscle; if induced by excess nonesterified fatty acids and circulating triacylglycerol
4788 PPARA interacts (colocalizes) with PPARGC1A
4894 LPIN1 increases_expression of PPARA in nucleus
5110 PPARA affects_activity of TRIB3 in liver
5126 LPIN1B increases_expression of PPARA
45968 PPARGC1 affects_activity of PPARA
19770177 Diabetes mellitus, type II
Obesity
Insulin resistance
868
5199 SIRT1 increases_expression of PPARA in liver; on high-fat diet, if SIRT1 is overexpressed
18840364 Diabetes mellitus, type II
Insulin resistance
947
5780 SIRT1 increases_activity of PPARA
5787 SIRT1 interacts (colocalizes) with PPARA
5789 fasting increases_activity of PPARA
5790 PPARA increases_activity of lipid catabolic process in white adipose tissue
5791 PPARA increases_activity of fatty acid beta-oxidation in liver
5792 PPARA increases_activity of ketone body biosynthetic process in liver
5812 PPARA increases_expression of CPT1A
5814 PPARA increases_expression of CPT2
5815 PPARA increases_expression of ACAD
5816 PPARA increases_expression of ACOX1
5817 PPARA increases_expression of CD36
5818 PPARA increases_expression of Cyp4A14
5819 PPARA increases_expression of Cyp4A10
5844 PPARA increases_expression of CYCS
5845 PPARA increases_expression of COX4
5847 PPARA increases_expression of COX5B
13194 PPARA increases_activity of fatty acid beta-oxidation in liver
19356714 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
1,519
10767 Polyunsaturated fatty acid, omega-3 decreases_expression of PPARA
19211925 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
1,592
11541 inflammatory response decreases_expression of PPARA
11569 Chrysin decreases_expression of PPARA
11639 PPARA affects_activity of mRNA transcription
11640 PPARA affects_activity of mRNA transcription
20816778 Diabetes mellitus, type II
Insulin resistance
1,668
12301 IKBKG affects_expression of PPARA in liver
18216263 Hepatocellular carcinoma
Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
1,888
14330 PPARA affects_activity of inflammatory response via close association with increased levels of inflammatory mediators during the aging
14331 aging affects_activity of PPARA
14339 PPARA decreases_activity of inflammatory response by inhibiting the expression of inflammatory genes, such as cytokines, matrix metalloproteases
14356 PPARA decreases_expression of Cytokine
18313368 Alzheimer disease
2,266
19349 SPP1 NOT affects_expression of PPARA in liver
21562757 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
2,270
19401 ACADVL affects_activity of PPARA
20444420 Diabetes mellitus, type II
Obesity
Insulin resistance
2,784
25738 Metformin increases_expression of PPARA in pancreas, in pancreatic islets
20972533 Diabetes mellitus, type II
Insulin resistance
3,387
31622 Clofibrate increases_activity of PPARA
11802770 Diabetes mellitus, type II
Carnitine deficiency, systemic primary
Insulin resistance
3,388
31822 PPARA increases_expression of BBOX1
31823 PPARA increases_expression of ALDH9A1
31824 PPARA increases_expression of SLC22A5
22134503 Diabetes mellitus, type II
Carnitine deficiency, systemic primary
Insulin resistance
Status epilepticus
Cardiovascular disease
3,418
31788 PPARA affects_activity of fatty acid transport
31790 PPARA affects_activity of fatty acid beta-oxidation
11257506 Diabetes mellitus, type II
Carnitine deficiency, systemic primary
Insulin resistance
3,471
32365 PPARA affects_quantity of Glucose
32378 PPARA affects_quantity of Glutamine
32382 PPARA affects_quantity of Alanine
32385 PPARA affects_quantity of Lactate
32387 PPARA affects_activity of fatty acid beta-oxidation
32388 PPARA affects_activity of ketone body biosynthetic process
32390 PPARA affects_activity of gluconeogenesis
32391 PPARA affects_activity of hypoglycemia after fasting
32393 PPARA affects_activity of tricarboxylic acid cycle
32394 PPARA affects_quantity of Carnitine
32397 PPARA affects_quantity of Short-chain acylcarnitine
32400 PPARA affects_quantity of Long-chain acyl-CoA
19875619 Diabetes mellitus, type II
Obesity
Insulin resistance
3,503
32511 PPARA affects_activity of abnormal circulating free fatty acids level
32513 PPARA affects_activity of insulin secretion
32525 PPARA affects_quantity of Acetylcarnitine in blood plasma, in liver, in skeletal muscle
32542 PPARA affects_quantity of Hydroxybutyrylcarnitine in blood plasma, in liver, in skeletal muscle
32545 PPARA affects_quantity of Succinylcarnitine in blood plasma, in liver, in skeletal muscle
32553 PPARA affects_quantity of Linoleylcarnitine
32554 PPARA affects_quantity of Octadecenylcarnitine
32555 PPARA affects_quantity of Palmitoylcarnitine
32557 PPARA affects_quantity of Octanoylcarnitine
32559 PPARA affects_quantity of O-Decanoyl-L-carnitine
32560 PPARA affects_quantity of Lauroylcarnitine
32561 PPARA affects_quantity of Isovalerylcarnitine in skeletal muscle
32563 PPARA NOT affects_quantity of Isovalerylcarnitine in blood plasma
32564 PPARA affects_quantity of Carnitine in blood plasma, in liver, in skeletal muscle
32569 PPARA affects_expression of BBOX1 in liver
32570 PPARA affects_expression of SLC22A5
32581 PPARA affects_quantity of Citrate in liver
32582 PPARA affects_quantity of Fumarate in liver
32583 PPARA affects_quantity of Malate in liver
32584 PPARA affects_quantity of 2-Oxoglutarate in liver
32595 PPARA affects_quantity of Succinate in skeletal muscle
32596 PPARA affects_quantity of 2-Oxoglutarate in skeletal muscle
32597 PPARA affects_quantity of Fumarate in skeletal muscle
32598 PPARA affects_quantity of Citrate in skeletal muscle
32599 PPARA affects_quantity of Malate in skeletal muscle
32606 PPARA affects_quantity of Alanine in blood plasma
32607 PPARA affects_quantity of Tyrosine in blood plasma
32609 PPARA affects_quantity of Glutamate in liver
32610 PPARA affects_quantity of Glutamine in liver
32612 PPARA affects_quantity of Aspartate in liver
32613 PPARA affects_quantity of Arginine in liver
32614 PPARA affects_quantity of Citrulline in liver
32615 PPARA affects_activity of incomplete fatty acid beta-oxidation
32617 PPARA affects_expression of IVD in skeletal muscle
32620 PPARA NOT affects_expression of HMGCL in skeletal muscle
32624 PPARA affects_expression of GOT1 in liver
32625 PPARA affects_expression of TAT in liver
32626 PPARA NOT affects_expression of GOT2 in liver
32627 PPARA affects_activity of carnitine biosynthetic process
32628 carnitine supplementation affects_activity of PPARA
18945875 Diabetes mellitus, type II
Insulin resistance
3,571
33418 NR1H4 affects_expression of PPARA in skeletal muscle
16446356 Diabetes mellitus, type II
Insulin resistance
3,617
34206 Colestimide NOT affects_expression of PPARA in liver
34207 Cholic acid NOT affects_expression of PPARA in liver
22952571 Diabetes mellitus, type II
Insulin resistance
3,619
34237 high-fat diet, salmon protein hydrolysate-based decreases_expression of PPARA in liver
21680746 Diabetes mellitus, type II
Insulin resistance
Metabolic syndrome
3,646
34643 NR1H4 increases_expression of PPARA
34644 PPARA increases_activity of fatty acid beta-oxidation
22187656 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
3,655
34745 PPARA increases_expression of SLC25A20
19577614 Diabetes mellitus, type II
Insulin resistance
3,892
39368 PPARA affects_activity of energy homeostasis
39370 PPARA affects_activity of fatty acid catabolic process
39371 PPARA affects_activity of ketone body biosynthetic process
39372 PPARA affects_activity of gluconeogenesis
39378 PPARA increases_quantity of Carnitine in liver
39379 PPARA affects_activity of carnitine metabolic process
39380 PPARA increases_expression of SLC22A5
39382 PPARA increases_expression of BBOX1
39383 PPARA increases_expression of ALDH9A1
39384 PPARA affects_activity of peroxisome fission in rodents
39388 PPARA affects_activity of Hepatocellular carcinoma in rodents
39396 PPARA NOT affects_activity of peroxisome fission in humans
39397 PPARA NOT affects_activity of Hepatocellular carcinoma in humans
39461 PPARA affects_expression of CPT1A
39463 PPARA affects_expression of CPT1B
39464 PPARA affects_expression of CPT1C
39465 PPARA affects_expression of SLC25A20
23150726 Diabetes mellitus, type II
Insulin resistance
3,933
39933 Naringenin increases_activity of PPARA
20811644 Diabetes mellitus, type II
Insulin resistance
3,950
40110 Naringenin increases_expression of PPARA
18690615 Diabetes mellitus, type II
Insulin resistance
4,129
42554 PPARA NOT affects_quantity of adipose tissue
42555 PPARA NOT affects_expression of LEP
8770873 Diabetes mellitus, type II
Insulin resistance
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