Search Results for "MME" - 94 interactions found in 29 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
613
3261 Metformin NOT affects_activity of MME
3262 Metformin NOT affects_quantity of MME
19237574 Diabetes mellitus, type II
Insulin resistance
2,076
16741 MME decreases_quantity of ACTH
16742 MME decreases_quantity of Alpha-MSH
17363457 Diabetes mellitus, type II
Insulin resistance
3,414
31851 APP (intracellular domain AICD) increases_expression of MME via promoter-binding; depending on cell type
22122663 Alzheimer disease
3,430
31932 aging decreases_quantity of MME concerning the steady-state levels; the steady-state levels of IDE and NEP are significantly higher in the cerebellum compared to the cortex and hippocampus
82499 aging increases_quantity of MME in the cerebellum ; or remain unaltered during aging
15708439 Alzheimer disease
3,440
32011 exercise increases_activity of MME
22563077 Alzheimer disease
3,657
34793 Sin-1 NOT affects_activity of MME in vitro
22227962 Alzheimer disease
3,761
37258 MME decreases_quantity of Amyloid beta peptide in type 2 microglia; by degrading Abeta
37282 IL4 increases_expression of MME
22970774 Alzheimer disease
3,792
37833 aging decreases_expression of MME in microglia; in older transgenic presenilin 1 (PS1)-APP mice
19464758 Alzheimer disease
4,090
42351 MME decreases_quantity of Amyloid beta peptide Neprilysin is mainly localized at the pre-synaptic areas of neurons and participates in Abeta degradation.
42352 Somatostatin increases_expression of MME at the cell membrane
42353 Alzheimer disease decreases_quantity of MME in AD hippocampus and AD cerebral cortex
42356 mild cognitive impairment decreases_quantity of MME in CSF
20158567 Alzheimer disease
4,869
48005 Amyloid beta peptide (42)-Al3+ complex decreases_expression of MME
21298039 Alzheimer disease
6,360
59606 MME decreases_quantity of Glucagon-like peptide 1
15655705 Diabetes mellitus, type II
Insulin resistance
8,197
82489 MME decreases_quantity of Amyloid beta peptide
82494 MME interacts (colocalizes) with MME in lipid rafts; forming a homodimer
82522 APP (intracellular domain AICD) increases_expression of MME
83010 response to cholesterol depletion decreases_expression of MME Cholesterol depletion in cells by MbetaCD
22737128 Alzheimer disease
8,232
83169 APP695 increases_expression of MME in a gamma-secretase- and AICD-dependent manner
83175 BACE1 increases_expression of MME
83178 APP695 increases_expression of MME in neuronal SH-SY5Y cells
83181 APP-p.KM670/671NL increases_expression of MME in SH-SY5Y cells expressing the Swedish mutant of APP(695); the Swedish mutant of APP(695), compared with wild-type APP(695) cells
83182 response to cholesterol depletion decreases_quantity of MME in cholesterol-depleted APP(695) cells
20961856 Alzheimer disease
8,779
91610 APP (intracellular domain AICD) affects_expression of MME
91635 APP695 increases_expression of MME in neuronal cell lines
91641 APP (intracellular domain AICD) increases_expression of MME
91646 Imatinib increases_quantity of MME via stabilising and elevating AICD levels
23684647 Alzheimer disease
10,371
107582 MME affects_activity of Spinocerebellar ataxia 43
107584 MME affects_activity of sensorimotor axonal polyneuropathy, late-onset
107585 MME affects_activity of ataxia, cerebellar
124220 MME affects_activity of pes cavus
124221 MME affects_activity of abnormal gait
124222 MME affects_activity of hypometric saccades
124224 MME affects_activity of dysarthria
124225 MME affects_activity of cerebellar vermis atrophy
27583304 Spinocerebellar ataxia 43
10,372
107586 MME affects_activity of Charcot-Marie-Tooth disease, axonal, type 2T
124227 MME affects_activity of axonal neuropathy, late-onset
124228 MME affects_activity of muscle weakness
124229 MME affects_activity of muscular atrophy
124231 MME affects_activity of abnormal gait
26991897 Charcot-Marie-Tooth disease, axonal, type 2T
10,373
107587 heart failure increases_activity of MME in cardiac muscle
107588 aortic valve stenosis increases_activity of MME in cardiac muscle
11804980 Cardiovascular disease
10,825
110372 MME affects_activity of Myocardial infarction
31269974 Myocardial infarction
11,717
116435 MME decreases_quantity of Angiotensin (1-7)
30404071 Diabetes mellitus, type II
Insulin resistance
11,751
116385 MME decreases_quantity of Angiotensin I
116896 MME increases_quantity of Angiotensin (1-7)
116897 MME decreases_quantity of Angiotensin (1-9)
15283675 Endocrine
11,776
116584 MME decreases_quantity of Angiotensin I
116585 MME increases_quantity of Angiotensin (1-7)
23463883 Diabetes mellitus, type II
Insulin resistance
Cardiovascular disease
12,027
117942 MME decreases_quantity of Angiotensin (1-12) in renal cortical membranes
117943 MME increases_quantity of Angiotensin (1-7) in renal cortical membranes
117944 MME increases_quantity of Angiotensin (1-4) in renal cortical membranes
22490446 Cardiovascular disease
12,029
118005 MME decreases_quantity of Angiotensin (1-9)
118006 MME increases_quantity of Angiotensin (1-7)
30934934 Diabetes mellitus, type II
Insulin resistance
Cardiovascular disease
12,056
118348 MME decreases_quantity of Angiotensin (1-9)
118350 MME increases_quantity of Angiotensin (1-7)
19065996 Diabetes mellitus, type II
Insulin resistance
12,286
120477 sex, male increases_activity of MME in blood serum; in younger males
28174624 Cardiovascular disease
12,344
120835 atherosclerotic lesions increases_expression of MME
27754866 Cardiovascular disease
12,867
123403 Progesterone increases_expression of MME in human endometrium
123404 Estradiol increases_expression of MME in uterus as well as in rat brain and a neuroblastoma cell line
123440 Progesterone NOT affects_expression of MME concerning mRNA level
123453 Estradiol NOT affects_expression of MME in primary neuron cultures; concerning mRNA level
22962256 Alzheimer disease
13,042
124235 Obesity increases_quantity of MME
124237 MME affects_activity of diarrhea
124238 MME affects_activity of hypertension
124239 MME affects_activity of decreased insulin sensitivity
124240 MME affects_activity of pancreatic beta cell
124241 MME affects_activity of impaired glucose tolerance
124243 MME affects_activity of Diabetes mellitus, type II
124245 MME affects_activity of insulin secretion involved in cellular response to glucose stimulus
124248 MME affects_quantity of Bradykinin
124249 MME affects_quantity of CCK
124250 MME affects_quantity of GIP
124251 MME affects_quantity of Glucagon-like peptide 1
124252 MME affects_quantity of NPPA
124253 MME affects_quantity of NPPB
124254 MME affects_quantity of PPY
124255 MME affects_quantity of PYY
124256 MME affects_quantity of SCT
124257 MME affects_quantity of VIP
124258 MME affects_quantity of Adrenomedullin
124259 MME affects_quantity of Angiotensin II
124260 MME affects_quantity of Angiotensin (1-7)
124261 MME affects_quantity of Endothelin-1
124262 MME affects_quantity of Glucagon
124263 MME affects_quantity of IL1B
124264 MME affects_quantity of IAPP
124265 MME affects_quantity of Somatostatin
124270 MME increases_activity of renin-angiotensin system
31089754 Diabetes mellitus, type II
Insulin resistance
Cardiomyopathy, diabetic
13,049
124273 MME affects_activity of Alzheimer disease
31266021 Neurodegenerative disorder
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