Search Results for "MAPT" - 200 interactions found in 68 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
8
23 LRRK2 NOT interacts (colocalizes) with MAPT
16352719 Parkinson disease
40
92 SNCA interacts (colocalizes) with MAPT in axons of hippocampal neurons
94 SNCA increases_phosphorylation of MAPT by protein kinase A
45617 MAPT is localized in axon of hippocampal neurons
10464279 Parkinson disease
44
115 MAPT increases_quantity of alpha-synuclein inclusion body
118 SNCA increases_folding of MAPT
119 MAPT increases_folding of SNCA
120 SNCB NOT increases_folding of MAPT
12714745 Parkinson disease
Tauopathy
Synucleinopathy
45
121 SNCA-p.A53T increases_folding of MAPT in addition to alpha-synuclein aggregates
12714745 Parkinson disease 7, autosomal recessive early-onset
Parkinson disease
Tauopathy
Synucleinopathy
60
186 PARK2-p.C212Y increases_phosphorylation of MAPT
12446971 Parkinson disease 2, autosomal recessive juvenile
Parkinson disease
Tauopathy
61
188 MAPT interacts (colocalizes) with SNCA in Lewy bodies
12722831 Alzheimer disease
Parkinson disease
Diffuse Lewy Body disease
64
197 Insulin increases_phosphorylation of MAPT
9930729 Alzheimer disease
122
453 GSK3B increases_phosphorylation of MAPT
685 GBP decreases_phosphorylation of MAPT GBP binding inhibited GSK3B-mediated phosphorylation of the intact tau protein.
64421 Lithium decreases_phosphorylation of MAPT
11527574 Alzheimer disease
236
980 GSK3B interacts (colocalizes) with MAPT
981 MAPT decreases_expression of CTNNB1 if MAPT is overexpressed
14039 MAPT increases_activity of CTNNB1 if cotranfected with GSK3B
1899151 Alzheimer disease
324
1270 EPM2A decreases_phosphorylation of MAPT at Ser396 residue
1272 EPM2A interacts (colocalizes) with MAPT
19542233 Myoclonic epilepsy of Lafora
384
1576 LRRK2 increases_phosphorylation of MAPT although MAPT is not directly phosphorylated by LRRK2
19545277 Parkinson disease
397
1707 NIRKO mouse increases_phosphorylation of MAPT in brain; at Thr231;
1708 NIRKO mouse NOT increases_phosphorylation of MAPT in brain; at Ser202;
14981233 Alzheimer disease
409
1778 MAPT is localized in microtubule
11698390 Parkinson disease
418
1983 Alzheimer disease increases_phosphorylation of MAPT
19144826 Alzheimer disease
574
3041 GSK3B increases_phosphorylation of MAPT
3048 MAPT interacts (colocalizes) with PSEN1
17298085 Alzheimer disease
658
3532 FYN interacts (colocalizes) with MAPT
19337449 Alzheimer disease
662
3549 MAPT affects_activity of Parkinson disease
3554 MAPT affects_activity of Tauopathy
85928 MAPT affects_activity of Parkinson disease
19915575 Parkinson disease
Tauopathy
786
4400 HSP70 affects_activity of MAPT
4407 HSP70 interacts (colocalizes) with MAPT
4408 HSP70 affects_quantity of MAPT
19793966 Alzheimer disease
792
4685 HSPB1 NOT interacts (colocalizes) with MAPT
4687 HSPB1 increases_phosphorylation of MAPT at Ser262
4690 MAPT interacts (colocalizes) with HSP70
4697 AKT1 affects_phosphorylation of MAPT
19449461 Alzheimer disease
812
4698 HSP70 affects_quantity of MAPT (level of soluble, MT-bound, or phosphorylated TAU)
4699 HSP90 affects_quantity of MAPT (level of soluble, MT-bound, or phosphorylated TAU)
12522269 Alzheimer disease
814
4704 STUB1 affects_ubiquitination/sumoylation of MAPT
4705 STUB1 affects_quantity of MAPT
4706 HSP70 affects_ubiquitination/sumoylation of MAPT
4707 HSP70 affects_quantity of MAPT
14962978 Alzheimer disease
822
4753 HSPB1 increases_phosphorylation of MAPT if HSPB1/HSP27 is overexpressed
4754 CRYAB decreases_phosphorylation of MAPT if alphaB-crystallin is overexpressed
18061943 Alzheimer disease
887
5233 MAPT NOT interacts (colocalizes) with HSPA8
5240 MAPT interacts (colocalizes) with microtubule via carboxyl end of TAU
15615647 Alzheimer disease
Tauopathy
895
5286 GSK3B affects_phosphorylation of MAPT
5293 CDK5 affects_phosphorylation of MAPT
5332 UBE2D2 affects_ubiquitination/sumoylation of MAPT
87307 MAPT is_part_of CHIP-HSC70-TAU-UBCH5B complex if TAU/MAPT is hyperphosphorylated
14612456 Alzheimer disease
905
5386 CASP1 increases_processing of MAPT at TAU-Asp421
5390 CASP3 increases_processing of MAPT at TAU-Asp421
5391 CASP6 increases_processing of MAPT at TAU-Asp421
5392 CASP7 increases_processing of MAPT at TAU-Asp421
5393 CASP8 increases_processing of MAPT at TAU-Asp421
12888622 Alzheimer disease
907
5404 CASP3 increases_processing of MAPT at TAU-Asp421
5406 CASP6 increases_processing of MAPT at TAU-Asp421
20357768 Alzheimer disease
Tauopathy
920
5554 PARK2 interacts (colocalizes) with MAPT
5556 PARK2 NOT increases_ubiquitination/sumoylation of MAPT
18248624 Parkinson disease
1,007
6287 decreased SIRT1 level increases_quantity of MAPT in cerebral cortex of AD patients
19104446 Alzheimer disease
1,011
6306 PARK7-p.L166P increases_expression of MAPT
16115732 Parkinson disease
Tauopathy
1,051
6597 CSNK1D interacts (colocalizes) with MAPT
10924763 Alzheimer disease
Dementia, Lewy body
Pick disease of brain
Down syndrome
Amyotrophic lateral sclerosis
Parkinson disease
Parkinsonism-dementia of Guam
Supranuclear palsy, progressive, 1
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