Search Results for "IGF1" - 123 interactions found in 71 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
98
326 SOD1-p.G93A increases_quantity of IGF1 in microglia cultures
19672969 Amyotrophic lateral sclerosis
116
391 IGF1 increases_activity of AKT1
394 IGF1 affects_phosphorylation of AKT1 at Thr308 and Ser473
8978681 Alzheimer disease
122
678 IGF1 decreases_activity of GSK3B by increased Ser9 phosphorylation
12930 IGF1 increases_phosphorylation of GSK3B at Ser9
50125 IGF1 increases_phosphorylation of GSK3B at Ser9
11527574 Alzheimer disease
457
2062 IGF1 affects_activity of oligodendrocyte development
19712582 Alzheimer disease
1,290
8819 SOD1-p.G93A increases_expression of IGF1 in spinal cord microglia
8823 IL4 increases_quantity of IGF1 in spinal cord microglia
18997009 Amyotrophic lateral sclerosis
1,343
9165 SOD1-p.G93A decreases_quantity of IGF1 in microglia; with or without LPS stimulation
17555556 Amyotrophic lateral sclerosis
1,344
9167 SOD1-p.G93A decreases_quantity of IGF1 in microglia/motoneuron co-cultures
17555556 Amyotrophic lateral sclerosis
1,513
10710 Resveratrol decreases_quantity of IGF1 in mice on high-calorie diet
17086191 Diabetes mellitus, type II
Insulin resistance
1,654
12186 Tg2576 mouse increases_expression of IGF1 in hippocampus
12196559 Alzheimer disease
1,665
12279 MAPK8 affects_quantity of IGF1
20231445 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
2,809
25905 IGF1 affects_activity of Diabetes mellitus, type II
21059863 Diabetes mellitus, type II
Insulin resistance
2,810
25917 IGF1 increases_activity of Insulin-like growth factor 1 receptor in pancreas, in pancreatic beta cells
20947509 Diabetes mellitus, type II
Insulin resistance
2,814
25952 increased circulating insulin level increases_quantity of IGF1 in liver
26006 IGF1 increases_activity of Insulin-like growth factor 1 receptor
26057 increased circulating insulin level increases_quantity of IGF1
26058 Obesity increases_quantity of IGF1
26110 IGF1 increases_activity of Insulin-like growth factor 1 receptor
26111 IGF1 increases_activity of INSR-A - IGF1R hybrid complex
26112 IGF1 increases_activity of INSR-B - IGF1R hybrid complex
21912508 Diabetes mellitus, type II
Cancer
Insulin resistance
Metabolic syndrome
2,889
26556 IGF1 increases_activity of positive regulation of mitotic nuclear division
18172327 Colorectal cancer
Diabetes mellitus, type II
Insulin resistance
2,935
26814 IGF1 increases_expression of HIF1A
26817 IGF1 affects_activity of phosphatidylinositol 3-kinase signaling
22249478 Diabetes mellitus, type II
Insulin resistance
3,073
28248 N-Nitrosodiethylamine decreases_expression of IGF1 in temporal lobe
20387270 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
3,131
28873 LEP NOT affects_quantity of IGF1
28903 fasting decreases_quantity of IGF1
16714386 Diabetes mellitus, type II
Insulin resistance
3,388
31862 carnitine supplementation increases_expression of IGF1 in liver
31865 Carnitine increases_quantity of IGF1 in blood plasma
22134503 Diabetes mellitus, type II
Carnitine deficiency, systemic primary
Insulin resistance
Status epilepticus
Cardiovascular disease
3,512
32658 Obesity decreases_quantity of IGF1 in blood serum
19356713 Diabetes mellitus, type II
Obesity
Insulin resistance
3,651
34718 IGF1 affects_quantity of Glycine
34719 IGF1 affects_quantity of LysoPC(18:2)
23010998 Diabetes mellitus, type II
Insulin resistance
3,686
35455 prenatal caffeine ingestion decreases_expression of IGF1 in fetal liver
22583948 Diabetes mellitus, type II
Insulin resistance
3,794
37579 obese Zucker rat decreases_expression of IGF1 in skeletal muscle
20959535 Diabetes mellitus, type II
Insulin resistance
3,977
40440 prenatal growth retardation decreases_quantity of IGF1 in fetus
11788666 Diabetes mellitus, type II
Insulin resistance
4,595
45716 aging decreases_quantity of IGF1
9215295 Diabetes mellitus, type II
Insulin resistance
5,275
51579 NT-PPARGC1A-a increases_expression of IGF1
25136584 Diabetes mellitus, type II
Insulin resistance
5,300
51939 NT-PPARGC1A-b increases_expression of IGF1 in skeletal muscle
51940 PPARGC1A-a NOT affects_expression of IGF1 in skeletal muscle
51953 resistance exercise NOT affects_expression of IGF1 in skeletal muscle
51954 endurance exercise NOT affects_expression of IGF1 in skeletal muscle
23217713 Diabetes mellitus, type II
Insulin resistance
5,350
52315 IGF1 interacts (colocalizes) with IGF1R
52316 IGF1 interacts (colocalizes) with Insulin
17315038 Metabolic
5,441
53113 LRP5 affects_expression of IGF1 in pancreas, in pancreatic islets
12509515 Diabetes mellitus, type II
Insulin resistance
5,448
53175 IGF1 NOT increases_activity of DNA biosynthetic process in pancreas, in pancreatic islets
53186 IGF1 increases_expression of INS in pancreas, in pancreatic islets; via GSK3B
53187 IGF1 increases_expression of PDX1 in pancreas, in pancreatic islets; via GSK3B
53188 IGF1 increases_expression of NKX6-1 in pancreas, in pancreatic islets; via GSK3B
53189 IGF1 increases_expression of NKX2-2 in pancreas, in pancreatic islets; via GSK3B
23650507 Diabetes mellitus, type II
Insulin resistance
5,740
54360 PDX1 rs193922360 decreases_quantity of IGF1 in homozygous mutation carriers
20009086 Diabetes mellitus, type II
Diabetes mellitus, permanent neonatal
Insulin resistance
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