Search Results for "HIF1A" - 177 interactions found in 81 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
217
873 CNS ischemia increases_quantity of HIF1A
11029549 Amyotrophic lateral sclerosis
289
1170 response to hypoxia increases_expression of HIF1A already detectable after 4 h at 1% O(2)
1171 HIF1A increases_expression of ANG
19444281 Amyotrophic lateral sclerosis
379
1559 Lipophilic metal chelator DP-109 increases_quantity of HIF1A in SOD1(G93A) transgenic mice
1561 Lipophilic metal chelator DP-460 increases_quantity of HIF1A in SOD1(G93A) transgenic mice
17630988 Amyotrophic lateral sclerosis
655
3489 (5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline) increases_expression of HIF1A
3490 (5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline) increases_quantity of HIF1A
3491 (5-[4-propargylpiperazin-1-ylmethyl]-8-hydroxyquinoline) increases_expression of HIF1A
3492 (5-[4-propargylpiperazin-1-ylmethyl]-8-hydroxyquinoline) increases_quantity of HIF1A
19638399 Amyotrophic lateral sclerosis
1,321
9031 response to hypoxia increases_activity of HIF1A
9033 HIF1A affects_expression of APH1A HIF-1 activated by hypoxia
9034 HIF1A affects_quantity of Amyloid beta peptide
9035 HIF1A affects_activity of Gamma-secretase complex
24457 Nickel increases_quantity of HIF1A
24458 HIF1A interacts (colocalizes) with ARNT
24459 HIF1A is_part_of ARNT-HIF1A complex
16645044 Alzheimer disease
1,377
9710 HIF1A interacts (colocalizes) with BACE1 (promoter)
9740 HIF1A increases_expression of BACE1 in neuronal cells; if HIF1A is overexpressed, via binding to BACE1 promoter;
9750 HIF1A interacts (colocalizes) with APH1A (promoter) HIF-1alpha binds to the promoter of anterior pharynx-defective phenotype (APH-1).
9751 HIF1A increases_expression of APH1A
20552043 Alzheimer disease
1,531
10914 HIF1A decreases_activity of neuron death
20649842 Parkinson disease
1,532
10918 response to hypoxia increases_activity of HIF1A
10919 HPH decreases_activity of HIF1A
20649842 Parkinson disease
1,800
13502 HIF1A interacts (colocalizes) with SP1
15780936 Neurological
2,589
24432 ATM affects_expression of HIF1A
20676049 Diabetes mellitus, type II
Ataxia-telangiectasia
Insulin resistance
2,935
26813 IL1B increases_quantity of HIF1A
26814 IGF1 increases_expression of HIF1A
26815 IGF2 NOT affects_quantity of HIF1A
22249478 Diabetes mellitus, type II
Insulin resistance
3,432
31945 ElonginB/C-CUL2-VHL-RBX1 complex decreases_activity of HIF1A
21942715 von Hippel-Lindau syndrome
3,470
32427 response to hypoxia increases_quantity of HIF1A
19187226 Hematological
3,473
32317 COMMD1 decreases_activity of HIF1A
19220812 Metabolic
Major depressive disorder
3,494
32445 COMMD1 interacts (colocalizes) with HIF1A
32447 HIF1A is_part_of ARNT-HIF1A complex
32449 COMMD1 decreases_expression of HIF1A
20458141 Cancer
3,495
32458 AKT1 increases_quantity of HIF1A
32459 PIK3CA increases_quantity of HIF1A
12764143 Hepatocellular carcinoma
3,496
32463 NF-kappaB complex increases_expression of HIF1A
32464 IKBKB increases_expression of HIF1A
18432192 Immunological
3,497
32471 HIF1A increases_activity of inflammatory response
12628185 Neurological
3,500
32487 PHD-LIMD1-VHL complex decreases_quantity of HIF1A
22286099 Endocrine
3,542
32951 response to hypoxia increases_expression of HIF1A
7539918 Neurological
3,622
34322 Triiodothyronine increases_expression of HIF1A in fibroblasts
34324 HIF1A affects_activity of canonical glycolysis
34325 HIF1A increases_expression of SLC2A1
34326 HIF1A increases_expression of SLC16A3
21941681 Diabetes mellitus, type II
Insulin resistance
Hypothyroidism
Hyperthyroidism
3,795
37658 HIF1A interacts (colocalizes) with mTORC1 complex
18765678 Diabetes mellitus, type II
Insulin resistance
4,051
41801 HIF1A increases_expression of EWSR1
20442286 Ewing sarcoma
4,096
42354 HIF1A increases_expression of POMC
21814490 Diabetes mellitus, type II
Insulin resistance
4,107
42396 HIF1A increases_expression of LEP
17591803 Colorectal cancer
Diabetes mellitus, type II
Insulin resistance
4,109
42399 HIF1A increases_expression of LEP
12215445 Diabetes mellitus, type II
Insulin resistance
4,137
42677 Diabetes mellitus, type II decreases_expression of HIF1A in pancreas, in pancreatic islet
16096055 Diabetes mellitus, type II
Insulin resistance
4,139
42684 HIF1A is_expressed_in pancreatic islet in normoxic beta cells and islets
42686 Diabetes mellitus, type II decreases_expression of HIF1A in pancreas, in pancreatic islet
42687 HIF1A interacts (colocalizes) with ARNT in pancreas, in pancreatic islet
42699 HIF1A increases_expression of HNF4A in pancreas, in pancreatic islet
42702 HIF1A increases_expression of SLC2A1 in pancreas, in pancreatic islet
42703 HIF1A increases_expression of SLC2A2 in pancreas, in pancreatic islet
42704 HIF1A increases_expression of AKT2 in pancreas, in pancreatic islet
42705 HIF1A increases_expression of IRS2 in pancreas, in pancreatic islet
42709 Diabetes mellitus, type II decreases_expression of HIF1A in pancreas, in pancreatic islet
20440072 Diabetes mellitus, type II
Insulin resistance
4,140
42685 HIF1A interacts (colocalizes) with ARNT
42689 HIF1A affects_activity of impaired glucose tolerance
42690 HIF1A affects_activity of reduced pancreatic beta cell function
42691 HIF1A affects_expression of SLC2A2 in pancreas, in pancreatic beta cells
42692 HIF1A affects_expression of GCK in pancreas, in pancreatic beta cells
42693 HIF1A affects_expression of GPI in pancreas, in pancreatic beta cells
42694 HIF1A affects_expression of PFK in pancreas, in pancreatic beta cells
42695 HIF1A affects_expression of HNF4A in pancreas, in pancreatic beta cells
42696 HIF1A affects_expression of PGAM2 in pancreas, in pancreatic beta cells
42697 HIF1A affects_expression of AKT2 in pancreas, in pancreatic beta cells
42698 HIF1A affects_activity of decreased intracellular ATP level in pancreas, in pancreatic beta cells
42708 HIF1A increases_expression of ARNT in pancreas, in pancreatic beta cells
42717 Iron chelator increases_activity of HIF1A in pancreas, in pancreatic beta cells
42724 Iron decreases_expression of HIF1A in pancreas, in pancreatic beta cells
20440072 Diabetes mellitus, type II
Insulin resistance
4,142
42741 response to hypoxia increases_expression of HIF1A in liver
22051049 Diabetes mellitus, type II
Insulin resistance
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