Search Results for "GRM5" - 64 interactions found in 9 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
3,445
32146 carnitine supplementation increases_expression of GRM5 in liver; 7.5 fold
22040461 Diabetes mellitus, type II
Insulin resistance
3,778
37155 high-fat diet increases_expression of GRM5
15983191 Diabetes mellitus, type II
Insulin resistance
4,719
49373 GRM5 interacts (colocalizes) with PLCB1 through Galphaq proteins;
21441996 Neurological
4,891
48318 mir-137 affects_expression of GRM5
23637704 Schizophrenia
4,954
48949 Schizophrenia NOT affects_quantity of GRM5
48950 GRM5 affects_activity of glutamate receptor signaling pathway through the NMDA receptor (NMDAR)
48951 GRM5 affects_activity of NMDA receptor complex
23462049 Schizophrenia
4,964
49008 GRM5 interacts (colocalizes) with NMDA receptor complex in many parts of the brain including the hippocampus, striatum and the neocortex; via the scaffolding proteins Homer (via Preso1), SH3 and multiple ankyrin repeat domains (SHANK), guanylate-kinase-associated (GKAP, also known as SAPAP) and post-synaptic density 95 (PSD-95) in the post-synaptic density (PSD);
49009 GRM5 interacts (colocalizes) with Glutamate
49291 Glutamate increases_phosphorylation of GRM5
49292 GRM5 increases_activity of G-alpha-q/11 complex
49331 Calcineurin decreases_phosphorylation of GRM5
49333 GRM5 is_expressed_in cerebral cortex
49334 GRM5 is_expressed_in hippocampus
49335 GRM5 is_expressed_in nucleus accumbens
49336 GRM5 is_expressed_in lateral septum
49337 GRM5 is_expressed_in striatum
49338 GRM5 is_expressed_in hypothalamus
49339 GRM5 is_expressed_in amygdala
49340 GRM5 is_expressed_in astrocyte
49341 GRM5 is_expressed_in oligodendrocyte
49342 GRM5 is_expressed_in microglia
49343 GRM5 is_expressed_in stemprogenitor cell
49344 GRM5 is_expressed_in pyramidal cell
49345 GRM5 is_expressed_in interneuron of the cortex
49346 NCDN interacts (colocalizes) with GRM5 by binding directly to the C-terminus of mGluR5
49347 GRASP interacts (colocalizes) with GRM5 bind directly to the C-terminus of mGluR5
49348 CALM1 interacts (colocalizes) with GRM5 bind directly to the C-terminus of mGluR5
49380 GRM5 affects_activity of NMDA receptor complex
49383 GRM5 affects_activity of long term synaptic depression
49386 GRM5 affects_activity of long-term synaptic potentiation
49387 GRM5 affects_activity of cognition
49389 RGS4 decreases_activity of GRM5
49391 Schizophrenia NOT affects_quantity of GRM5 in the thalamus, hippocampus, PFC and striatum; of patients with schizophrenia
49399 Haloperidol increases_expression of GRM5 typical APD treatment;
49410 Sertinadole increases_expression of GRM5 atypical APD treatment;
49490 Apomorphine decreases_expression of GRM5
49491 DRD2 interacts (colocalizes) with GRM5 in the striatum, particularly at the corticostriatal glutamate synapse
49496 CDPPB affects_activity of GRM5
49498 DFB affects_activity of GRM5
49503 ADX47273 affects_activity of GRM5
49520 CHPG affects_activity of GRM5
49522 MK801 affects_activity of GRM5
49528 MPEP affects_activity of GRM5
49534 LSN2463359 affects_activity of GRM5
49536 MPPA affects_activity of GRM5
49538 VU0359640 affects_activity of GRM5
49541 CPPZ affects_activity of GRM5
49545 VU0364289 affects_activity of GRM5
23253944 Schizophrenia
5,025
49587 GRM5 affects_activity of NMDA receptor complex via the activity-dependent NR2B-NR2A switch
49589 GRM5 affects_quantity of GRIN2A
49590 GRM5 affects_quantity of GRIN2B
21521618 Schizophrenia
5,037
49690 GRM5 increases_activity of NMDA receptor complex via one or a combination of various scaffolding proteins (e.g., Homer, Shank, GKAP and PSD-95), if GRM5 is activated;
49693 GRM5 affects_activity of brain development
49694 GRM5 affects_activity of regulation of stem cell proliferation
49695 GRM5 affects_activity of regulation of stem cell migration
49696 GRM5 affects_quantity of GRIN2A in hippocampus
49697 GRM5 affects_quantity of GRIN2B in hippocampus
49701 VU0360172 affects_activity of GRM5
49702 LN2463359 affects_activity of GRM5
49703 LN2814617 affects_activity of GRM5
49706 DRD2 interacts (colocalizes) with GRM5 in the striatum, particularly at the corticostriatal glutamate synapse
24024939 Schizophrenia
5,110
50238 GRM5 affects_activity of BMAA
50239 GRM5 affects_activity of PP2A complex if BMAA (beta-N-methylamino-L-alanine) treated
24395787 Tauopathy
Parkinsonism-dementia of Guam
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