Search Results for "FOXO1" - 220 interactions found in 70 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
368
1513 Insulin resistance decreases_phosphorylation of FOXO1 in liver
12628 HSPA5 affects_phosphorylation of FOXO1 in liver
19363290 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
714
4033 Insulin decreases_activity of FOXO1
4035 Insulin increases_phosphorylation of FOXO1 via PI3K-dependent pathway
4036 FOXO1 increases_expression of MTTP in liver
4038 Insulin resistance increases_activity of FOXO1
4039 FOXO1 affects_activity of Fatty liver disease, nonalcoholic
4041 FOXO1 increases_expression of PCK1
4043 FOXO1 increases_expression of G6PC
4084 fasting increases_expression of FOXO1
4085 insulin receptor signaling pathway decreases_activity of FOXO1 in liver
13067 fasting increases_transport of FOXO1 into the nucleus
13069 feeding increases_phosphorylation of FOXO1
13070 feeding increases_transport of FOXO1 into the cytoplasm
13072 FOXO1 increases_activity of gluconeogenesis in liver
13073 Insulin resistance increases_activity of FOXO1 in liver
13074 FOXO1 increases_activity of VLDL secretion in liver
13075 FOXO1 affects_activity of hyperglycemia
13076 FOXO1 affects_activity of increased circulating triglyceride level
18927507 Diabetes mellitus, type II
Abetalipoproteinemia
Insulin resistance
Fatty liver disease, nonalcoholic
Cardiovascular disease
824
4852 PPARGC1A increases_activity of FOXO1 in liver
45974 PPARGC1 affects_activity of FOXO1
19770177 Diabetes mellitus, type II
Obesity
Insulin resistance
868
5205 SIRT1 decreases_acetylation of FOXO1
5207 SIRT1 decreases_acetylation of FOXO1 in liver; if SIRT1 is overexpressed
18840364 Diabetes mellitus, type II
Insulin resistance
906
5478 SIRT1 affects_acetylation of FOXO1 if SIRT1 is knocked down in liver and adipose tissue of diabetic rats
19549853 Diabetes mellitus, type II
Insulin resistance
918
5574 prolonged fasting NOT affects_quantity of FOXO1 in liver
5577 FOXO1 increases_activity of gluconeogenesis in liver; after long-term fasting when CRTC2 is degraded
5669 SIRT1 increases_activity of FOXO1 during prolonged fasting
5671 FOXO1 affects_activity of glucose metabolic process
18849969 Diabetes mellitus, type II
Insulin resistance
1,186
7876 S-Nitroso-N-acetylpenicillamine decreases_phosphorylation of FOXO1
15632167 Diabetes mellitus, type II
Insulin resistance
1,518
10748 Curcumin increases_expression of FOXO1 in perigonadal white adipose tissue; in mouse models of obesity-related diabetes
18403477 Diabetes mellitus, type II
Obesity
Insulin resistance
1,674
12433 hyperglycemia increases_expression of FOXO1 in adipose tissue
15536073 Diabetes mellitus, type II
Insulin resistance
1,925
14882 exercise NOT affects_phosphorylation of FOXO1 in hypothalamus
14891 high-fat diet decreases_phosphorylation of FOXO1 in hypothalamus; at Ser residues of FOXO1
14897 exercise increases_phosphorylation of FOXO1 in hypothalamus; at Ser residues of FOXO1, after high-fat diet
20808781 Diabetes mellitus, type II
Obesity
Insulin resistance
2,266
19341 SPP1 affects_expression of FOXO1 in liver
19357 Obesity increases_expression of FOXO1 in liver
21562757 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
2,267
19368 hyperglycemia decreases_phosphorylation of FOXO1
21107520 Diabetes mellitus, type II
Obesity
Insulin resistance
2,451
22692 TCF7L2 affects_phosphorylation of FOXO1 in pancreas, in pancreatic islets
19386626 Diabetes mellitus, type II
Insulin resistance
3,569
33370 FOXO1 affects_expression of ABCG5 in liver
33371 FOXO1 affects_expression of ABCG8 in liver
33372 FOXO1 affects_expression of PCK1 in liver
33373 FOXO1 affects_expression of G6PC in liver
33374 FOXO1 affects_expression of IGFBP1 in liver
18587407 Diabetes mellitus, type II
Insulin resistance
3,570
33375 FOXO1 affects_expression of CYP7A1 in liver
33376 FOXO1 affects_expression of CYP7B1 in liver
33377 FOXO1 affects_expression of CYP27A1 in liver
18587407 Diabetes mellitus, type II
Insulin resistance
3,613
34093 Insulin increases_phosphorylation of FOXO1 in liver; at Thr24
34095 Taurocholate increases_phosphorylation of FOXO1 in liver; at Thr24
34096 Deoxycholic acid increases_phosphorylation of FOXO1 in liver; at Thr24
20305288 Diabetes mellitus, type II
Insulin resistance
3,615
34111 Cholic acid increases_expression of FOXO1 in brown adipose tissue
34112 Chenodeoxycholate increases_expression of FOXO1 in brown adipose tissue
16400329 Diabetes mellitus, type II
Obesity
Insulin resistance
3,930
39911 Naringenin NOT affects_quantity of FOXO1 in liver; in Ldlr-/- mice
19592617 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
4,370
44573 Melatonin decreases_acetylation of FOXO1 via SIRT1
19650880 Diabetes mellitus, type II
Insulin resistance
4,457
45259 AICAR increases_expression of FOXO1
45267 exercise increases_expression of FOXO1
15878932 Diabetes mellitus, type II
Insulin resistance
4,779
47308 SREBF1c NOT affects_phosphorylation of FOXO1 in liver; after reversion of hepatic steatosis
22932913 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
5,174
50625 Estradiol increases_phosphorylation of FOXO1 in cerebral blood vessels; at Ser256
24275351 Diabetes mellitus, type II
Insulin resistance
5,241
51049 PPARGC1A interacts (colocalizes) with FOXO1
20005308 Diabetes mellitus, type II
Insulin resistance
5,310
52353 PPARGC1A increases_activity of FOXO1 in liver
16122419 Diabetes mellitus, type II
Insulin resistance
Porphyria, acute hepatic
5,352
52319 PPARGC1A interacts (colocalizes) with FOXO1 in liver
52320 AKT1 interacts (colocalizes) with FOXO1 in liver
12754525 Metabolic
5,353
52321 FOXO1 affects_activity of gluconeogenesis in liver
24692138 Metabolic
5,365
52479 AKT1 increases_transport of FOXO1 from nucleus to cytoplasm; after dissociation from PPARGC1A
16122419 Porphyria variegata
Porphyria, congenital erythropoietic
Porphyria, acute hepatic
Porphyria, acute intermittent
Coproporphyria, hereditary
5,736
54313 SOX17 decreases_expression of FOXO1 in pancreas, in pancreatic beta cells
25144761 Diabetes mellitus, type II
Insulin resistance
5,769
54483 AKT1 decreases_activity of FOXO1
54485 FOXO1 decreases_expression of PDX1
54488 FOXO1 increases_activity of type B pancreatic cell apoptotic process
19817786 Diabetes mellitus, type II
Insulin resistance
6,214
59015 hypermethylation of CpG island affects_expression of FOXO1 in cancer, via colocalizing with the promoter of gene.
23965899 Cancer
Ovarian cancer
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