Search Results for "EDN1" - 54 interactions found in 24 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
122
679 EDN1 decreases_activity of GSK3B in myocytes; by phosphorylation of GSK3B at Ser9
680 EDN1 increases_phosphorylation of GSK3B at Ser9, hereby inhibiting GSK3B.
11527574 Alzheimer disease
2,104
17599 Major depressive disorder decreases_quantity of EDN1
20161799 Major depressive disorder
2,525
23522 EDN1 NOT decreases_quantity of Amyloid beta peptide
23530 EDN1 decreases_expression of CCL2 if Abeta-induced expression
23533 EDN1 decreases_expression of IL6 if Abeta-induced expression
23549 EDN1 affects_activity of inflammatory response
20937084 Alzheimer disease
2,547
23729 Schizophrenia affects_quantity of EDN1
20520744 Schizophrenia
4,736
46855 EDN1 interacts (colocalizes) with EDNRA
46856 EDN1 interacts (colocalizes) with EDNRB
47038 EDN1 increases_quantity of NOS3 via activation of ETB receptors and PI3K
47039 EDN1 increases_quantity of NO via activation of ETB receptors and PI3K
50712 EDN1 increases_expression of NOS3 via activation of ETB receptors and PI3K
15113749 Cardiovascular disease
4,737
46857 EDN1 increases_expression of NOS3 via ETA receptors (EDNRA)
10519149 Cardiovascular disease
4,739
46868 sFLT1 increases_expression of EDN1 in presence of TNF-alpha
21139021 Preeclampsia/eclampsia 1
Cardiovascular disease
4,741
46886 NO decreases_expression of EDN1
46887 sFLT1 increases_expression of EDN1 in kidney
22282588 Preeclampsia/eclampsia 1
Cardiovascular disease
4,747
47008 NO decreases_quantity of EDN1 in endothelial cells
2153712 Metabolic
Cardiovascular disease
4,749
47033 ECE1 increases_processing of EDN1
9396733 Metabolic
Cardiovascular disease
4,750
47034 EDN1 interacts (colocalizes) with EDNRA
47035 EDN1 interacts (colocalizes) with EDNRB
7672512 Metabolic
Cardiovascular disease
4,971
49151 EDN1 increases_activity of foam cell differentiation in rat bone marrow-derived macrophages
49152 EDN1 decreases_quantity of ABCG1 in rat bone marrow-derived macrophages
49156 EDN1 decreases_activity of cholesterol efflux in rat bone marrow-derived macrophages
49158 EDN1 NOT affects_expression of ABCG1 in rat bone marrow-derived macrophages
49159 EDN1 increases_activity of EDNRA in rat bone marrow-derived macrophages
49160 EDN1 increases_activity of EDNRB in rat bone marrow-derived macrophages
49179 EDN1 increases_activity of Calpain in rat bone marrow-derived macrophages
49183 EDN1 NOT affects_quantity of CD36 in rat bone marrow-derived macrophages
49184 EDN1 NOT affects_quantity of SCARB1 in rat bone marrow-derived macrophages
49185 EDN1 NOT affects_quantity of MSR1 in rat bone marrow-derived macrophages
49186 EDN1 NOT affects_quantity of ABCA1 in rat bone marrow-derived macrophages
21520072 Cardiovascular disease
Atherosclerosis
5,012
49444 OLR1 increases_expression of EDN1
49452 OLR1 increases_quantity of EDN1
49453 CD40 signaling pathway increases_expression of EDN1
49454 CD40 signaling pathway increases_quantity of EDN1
15838273 Cardiovascular disease
Atherosclerosis
5,884
55621 pulmonary hypertension increases_expression of EDN1 in lung
24124488 Pulmonary hypertension
Lung disease
5,909
55793 EDN1 decreases_activity of vasodilation
55794 response to hypoxia increases_expression of EDN1
55796 PGF increases_expression of EDN1 in a dermal microvascular endothelial cell line (HMEC-1)
55808 mir-648 decreases_expression of EDN1 in endothelial cells
55809 mir-648 decreases_quantity of EDN1 in endothelial cells
25403488 Osteoarthritis
Sickle cell anemia
6,150
57541 hyperglycemia increases_expression of EDN1 in left ventricular myocardium; under poor hyperglycemic control
19367030 Diabetes mellitus, type II
Insulin resistance
Cardiomyopathy, diabetic
7,140
70308 GLIS2 affects_expression of EDN1
Nephronophthisis 7
10,043
104849 CASZ1 affects_expression of EDN1 in heart
25190801 Cardiovascular disease
Chromosome 1p36 deletion syndrome
10,316
107080 Monocrotaline increases_expression of EDN1
107085 EDN1 increases_expression of NOX4 in pulmonary artery smooth muscle cells
107086 EDN1 decreases_expression of GPX1 in pulmonary artery smooth muscle cells
107087 EDN1 increases_quantity of Reactive oxygen species in pulmonary artery smooth muscle cells
30274504 Pulmonary hypertension
12,012
117683 EDN1 NOT increases_activity of exosomal secretion in cardiac fibroblasts
26497614 Cardiovascular disease
12,064
118451 AGTR1 increases_activity of EDN1
19065996 Diabetes mellitus, type II
Insulin resistance
12,362
121218 Angiotensin (1-7) affects_activity of EDN1
24450744 Diabetes mellitus, type II
Insulin resistance
12,465
121623 UCN3 decreases_quantity of EDN1 in blood plasma; in experimental heart failure
16825287 Cardiovascular disease
13,337
125877 SARS-CoV-2 infection affects_expression of EDN1
COVID-19
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