Search Results for "CHRM3" - 80 interactions found in 21 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
2,121
17462 AD11 anti-NGF mouse affects_expression of CHRM3
19604602 Alzheimer disease
4,120
42441 Aripiprazole NOT interacts (colocalizes) with CHRM3 in pancreas
19285836 Diabetes mellitus, type II
Insulin resistance
Major depressive disorder
4,150
42809 CHRM3 is_expressed_in brain
42810 CHRM3 is_expressed_in pancreatic islet
42814 CHRM3 increases_activity of insulin secretion involved in cellular response to glucose stimulus
42817 CHRM3 increases_activity of glucagon secretion
42818 CHRM3 affects_activity of hyperglycemia
42819 CHRM3 affects_activity of impaired glucose tolerance
15220195 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,151
42821 CHRM3 increases_activity of PRKD1 via phosphorylation of CHRM3 at Ser744/748
42822 CHRM3 increases_activity of calcium ion import into cell
21078968 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,152
42825 Schizophrenia NOT affects_expression of CHRM3 in brain cortex
23423139 Schizophrenia
4,153
42827 CHRM3 decreases_activity of impaired glucose tolerance
42829 CHRM3 increases_activity of insulin secretion involved in cellular response to glucose stimulus
42830 CHRM3 decreases_activity of hyperglycemia
42832 CHRM3 affects_activity of glucose homeostasis
16753580 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,154
42840 CHRM3 affects_activity of binding density of CHRM3 in brain
21982116 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,155
42843 Olanzapine decreases_activity of CHRM3
10227113 Schizophrenia
4,158
42873 CHRM3 interacts (colocalizes) with RGS4
42876 RGS4 decreases_activity of CHRM3 in pancreas, in pancreatic beta cells
20385802 Diabetes mellitus, type II
Insulin resistance
4,276
43752 Olanzapine decreases_activity of CHRM3
23559402 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,658
46369 CHRM3 increases_expression of IRS2 via PLC, PKC, MEK1/2, and ERK1/2
46370 CHRM3 increases_activity of PLCB
23478411 Diabetes mellitus, type II
Insulin resistance
4,660
46381 Acetylcholine increases_activity of CHRM3 in pancreas, in pancreatic islets
46383 CHRM3 decreases_quantity of Phosphatidylinositol-4,5-bisphosphate in membrane, in pancreas, in pancreatic islets; catalyzed by phospholipase C
46392 CHRM3 increases_activity of PRKD1 in pancreas, in pancreatic islets; via a G-protein-independent, beta-arrestin-dependent process
46393 CHRM3 decreases_activity of MAPK13 in pancreas, in pancreatic islets
46395 ITPR increases_activity of CHRM3 in pancreas, in pancreatic islets
46446 ANK2 increases_activity of CHRM3 in pancreas, in pancreatic islets; via stabilization of CHRM3 by binding
46448 CHRM3 increases_activity of NALCN in pancreas, in pancreatic islets
46450 RGS4 decreases_activity of CHRM3 in pancreas, in pancreatic islets
46451 Carbachol increases_activity of CHRM3
21966580 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,686
46561 CHRM3 NOT affects_activity of Schizophrenia
46562 Olanzapine decreases_activity of CHRM3
46563 Clozapine decreases_activity of CHRM3
46564 Chlorpromazine interacts (colocalizes) with CHRM3
46568 CHRM3 is_expressed_in ventromedial hypothalamic nucleus in brain
46574 CHRM3 is_expressed_in arcuate nucleus in brain
46575 CHRM3 is_expressed_in dorsal vagal complex in brain
46576 increased circulating insulin level increases_expression of CHRM3 in brainstem
46577 hyperglycemia affects_activity of CHRM3 in cerebellum
46598 CHRM3 is_expressed_in pancreatic beta cell
46608 Acetylcholine increases_activity of CHRM3 in pancreas, in pancreatic islet beta cells
46628 CHRM3 increases_activity of ARRB in pancreas, in pancreatic islet beta cells; via phosphorylation of ARRB
46631 CHRM3 increases_activity of sodium ion import into the cell, in pancreas, in pancreatic islet beta cells
24114586 Bipolar disorder
Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,700
46637 PPP1R9B decreases_activity of CHRM3 in pancreas, in pancreatic islet
46641 RGS4 decreases_activity of CHRM3 in pancreas, in pancreatic islet; via PPP1R9B
22730439 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,701
46649 Carbachol increases_activity of CHRM3
46651 CHRM3 increases_activity of PLC
14985093 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,702
46653 CHRM3 affects_activity of decreased food intake
46654 CHRM3 affects_activity of Obesity
46655 CHRM3 affects_quantity of LEP in blood serum
46656 CHRM3 affects_quantity of Insulin in blood serum
46657 CHRM3 affects_expression of PMCH in hypothalamus
11242080 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,703
46658 CHRM3 is_expressed_in liver
46670 CHRM3 NOT affects_activity of abnormal liver physiology
46686 CHRM3 NOT affects_activity of gluconeogenesis in liver
46687 CHRM3 NOT affects_activity of glycogen catabolic process in liver
46692 CHRM3 NOT affects_expression of PCK1 in liver
46693 CHRM3 NOT affects_expression of G6PC in liver
46694 CHRM3 NOT affects_expression of PPARGC1A in liver
46695 CHRM3 NOT affects_expression of PPARGC1B in liver
46696 CHRM3 NOT affects_expression of PPARG in liver
46697 CHRM3 NOT affects_expression of CREB1 in liver
46698 CHRM3 NOT affects_expression of ACLY in liver
46699 CHRM3 NOT affects_expression of FASN in liver
46700 CHRM3 NOT affects_expression of ACOX in liver
46701 CHRM3 NOT affects_expression of CPT1A in liver
46702 CHRM3 NOT affects_expression of INSR in liver
46712 CHRM3 NOT affects_expression of IRS1 in liver
46713 CHRM3 NOT affects_expression of AKT2 in liver
46714 CHRM3 NOT affects_expression of GCK in liver
46715 CHRM3 NOT affects_expression of PC in liver
46716 CHRM3 NOT is_expressed_in Kupffer cell in liver
19752163 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,716
46733 CHRM3 decreases_activity of impaired glucose tolerance after high-fat diet
46734 CHRM3 increases_activity of increased circulating insulin level
46735 CHRM3 decreases_activity of hyperglycemia after high-fat diet
20843999 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,718
46738 CHRM3 affects_activity of insulin secretion
21696923 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
5,046
49725 CHRM3 affects_activity of Melanin-concentrating hormone
17130513 Metabolic
5,783
54568 Acetylcholine increases_activity of CHRM3 in pancreas, in pancreatic beta cells
54574 CHRM3 increases_quantity of Ca2+ in pancreas, in pancreatic beta cells
25697093 Diabetes mellitus, type II
Insulin resistance
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