Search Results for "Angiotensin II" - 431 interactions found in 121 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
1,978
15518 Angiotensin II increases_phosphorylation of IRS1 in cardiac muscle; at Tyr residues
15519 Angiotensin II increases_phosphorylation of IRS2 in cardiac muscle; at Tyr residues
15521 Angiotensin II affects_activity of JAK2
15525 Angiotensin II decreases_activity of Phosphatidylinositol 3-kinase in cardiac muscle
8901609 Diabetes mellitus, type II
Insulin resistance
Cardiovascular disease
1,985
15574 Angiotensin II increases_activity of hypertension
15575 Angiotensin II increases_activity of hyperglycemia if given in high doses
15576 Angiotensin II increases_activity of decreased blood flow velocity in pancreas, in pancreatic islets
15582 Saralasin decreases_activity of Angiotensin II
15587 Angiotensin II affects_activity of regulation of insulin secretion in pancreas
9498644 Diabetes mellitus, type II
Insulin resistance
1,987
15597 Angiotensin II decreases_activity of fat cell differentiation in adipose tissue
15599 Angiotensin II decreases_quantity of Lipid in adipose tissue
15602 Angiotensin II decreases_expression of PPARG in adipose tissue
15603 Angiotensin II decreases_expression of FASN in adipose tissue
12031955 Diabetes mellitus, type II
Insulin resistance
1,989
15664 ACE inhibitor affects_activity of Angiotensin II
15670 Angiotensin II decreases_activity of insulin receptor signaling pathway
15671 Angiotensin II increases_activity of Insulin resistance
15672 Angiotensin II increases_activity of response to oxidative stress
15673 ACE increases_quantity of Angiotensin II
15677 ACE inhibitor decreases_quantity of Angiotensin II
15680 Angiotensin II type 1 receptor blocker decreases_activity of Angiotensin II
20809236 Diabetes mellitus, type II
Stroke, ischemic
Myocardial infarction
Insulin resistance
Cardiovascular disease
Nephropathy, diabetic
Retinopathy, diabetic
Neuropathy, diabetic
1,996
15745 obese Zucker rat increases_quantity of Angiotensin II
15754 Irbesartan decreases_quantity of Angiotensin II in obese Zucker rats
19901849 Diabetes mellitus, type II
Obesity
Insulin resistance
Metabolic syndrome
2,002
15886 Angiotensin (1-7) decreases_activity of Angiotensin II in vascular smooth muscle
15891 Angiotensin II increases_activity of smooth muscle cell proliferation in vascular smooth muscle; via AGTR1
15892 Angiotensin II increases_activity of smooth muscle cell migration in vascular smooth muscle
15897 Angiotensin II increases_phosphorylation of MAPK3/1 in vascular smooth muscle
20808802 Diabetes mellitus, type II
Insulin resistance
2,009
15950 REN increases_quantity of Angiotensin II in Ren-2 rats
15958 response to oxidative stress affects_activity of Angiotensin II
15494608 Diabetes mellitus, type II
Insulin resistance
2,018
15989 Angiotensin II increases_activity of glucose import in adipose tissue; if insulin-stimulated, via AGTR1
15992 Angiotensin II increases_phosphorylation of Insulin receptor beta subunit in adipose tissue; at Tyr residues, if insulin-stimulated
15993 Angiotensin II increases_activity of Insulin receptor in adipose tissue; if insulin-stimulated
15994 Angiotensin II increases_phosphorylation of AKT1 in adipose tissue; if insulin-stimulated
15995 Angiotensin II increases_transport of SLC2A4 to the plasma membrane, in adipose tissue; if insulin-stimulated
15996 Angiotensin II increases_activity of insulin receptor signaling pathway in adipose tissue; if insulin-stimulated
15997 Angiotensin II increases_activity of increased insulin sensitivity in adipose tissue
15705782 Diabetes mellitus, type II
Insulin resistance
2,019
15998 Angiotensin II increases_quantity of GPD1 in white adipose tissue
15999 Angiotensin II increases_activity of fat cell proliferation in white adipose tissue; via prostacyclin
16000 Prostaglandin I2 affects_activity of Angiotensin II in white adipose tissue
11145613 Diabetes mellitus, type II
Insulin resistance
2,020
16025 Angiotensin II NOT affects_expression of AGT in adipose tissue
16026 Angiotensin II NOT affects_expression of REN in adipose tissue
16027 Angiotensin II NOT affects_expression of ACE in adipose tissue
16028 Angiotensin II NOT affects_expression of AGTR1 in adipose tissue
16029 Angiotensin II NOT affects_expression of AGTR2 in adipose tissue
12011658 Diabetes mellitus, type II
Obesity
Insulin resistance
2,038
16214 Angiotensin II increases_activity of NF-kappaB complex in skeletal muscle
16216 Angiotensin II increases_expression of TNF in skeletal muscle
16217 Angiotensin II decreases_activity of AKT1 in skeletal muscle; if stimulated by insulin
16218 Angiotensin II decreases transport of SLC2A4 to the plasma membrane, in skeletal muscle; if stimulated by insulin
18073321 Diabetes mellitus, type II
Insulin resistance
2,039
16265 Angiotensin II decreases_quantity of mitochondrion
16266 Angiotensin II increases_quantity of Reactive oxygen species in mitochondria
16267 Angiotensin II affects_activity of regulation of mitochondrial membrane potential
16279 Angiotensin II increases_activity of impaired glucose tolerance
16280 Angiotensin II NOT affects_activity of abnormal body weight
16281 Angiotensin II NOT affects_activity of abnormal food intake
16282 Angiotensin II increases_quantity of Triacylglycerol in skeletal muscle
16285 Angiotensin II decreases_expression of PPARGC1A via AGTR2
16286 Angiotensin II decreases_expression of TFAM via AGTR2
16293 Angiotensin II decreases_quantity of Mitochondrial respiratory chain complex V in mitochondria; via AGTR1 or AGTR2
16294 Angiotensin II decreases_quantity of Mitochondrial respiratory chain complex IV in mitochondria; via AGTR1 or AGTR2
16295 Angiotensin II decreases_expression of ACADM in mitochondria; via AGTR1 or AGTR2
19074984 Diabetes mellitus, type II
Insulin resistance
2,056
16437 ACE increases_quantity of Angiotensin II
2440624 Diabetes mellitus, type II
Insulin resistance
2,119
17327 Angiotensin II increases_activity of abnormal vascular endothelial cell physiology
17328 Angiotensin II increases_quantity of O2-
17329 Angiotensin II decreases_phosphorylation of VASP
17330 Angiotensin II decreases_activity of NO/cGMP-mediated signaling
17335 Angiotensin II decreases_activity of Nitroglycerin
17359 Angiotensin II increases_expression of NCF2 in membranes, in aorta, in cardiac muscle
17360 Angiotensin II increases_expression of RAC1 in membranes, in aorta, in cardiac muscle
17363 Angiotensin II increases_expression of NOX1 in membranes, in cardiac muscle
17365 Angiotensin II increases_expression of CYBB in aorta, in cardiac muscle
17366 Angiotensin II increases_expression of NCF1 in aorta, in cardiac muscle
17367 Angiotensin II increases_expression of CYBA in aorta, in cardiac muscle
17375 Angiotensin II increases_activity of NADPH oxidase complex
17386 Angiotensin II decreases_activity of NOS3 via uncoupling of the active homodimer
16940222 Diabetes mellitus, type II
Insulin resistance
2,122
17403 HDL decreases_activity of Angiotensin II
19273745 Diabetes mellitus, type II
Insulin resistance
2,172
18188 Obesity increases_quantity of Angiotensin II in blood
18191 Angiotensin II increases_activity of positive regulation of blood pressure
15191907 Diabetes mellitus, type II
Obesity
Insulin resistance
2,174
18199 Angiotensin II increases_activity of increased circulating aldosterone level
20130077 Diabetes mellitus, type II
Insulin resistance
2,175
18202 Angiotensin II NOT affects_activity of aldosterone biosynthetic process
14614137 Diabetes mellitus, type II
Obesity
Insulin resistance
2,178
18227 Angiotensin II increases_quantity of O2- in vascular smooth muscle
18228 Angiotensin II increases_activity of NADPH oxidase complex in vascular smooth muscle
18229 Angiotensin II increases_activity of NADH oxidase complex in vascular smooth muscle
8187280 Diabetes mellitus, type II
Insulin resistance
2,180
18244 Angiotensin II increases_activity of NADPH oxidase complex via CYBB
18245 Angiotensin II increases_activity of cardiac interstitial fibrosis via CYBB
18246 Angiotensin II increases_expression of FN1 via CYBB
18247 Angiotensin II increases_expression of COL1A1 via CYBB
18248 Angiotensin II increases_expression of CCN2 via CYBB
18249 Angiotensin II increases_activity of MMP2 via CYBB
18250 Angiotensin II increases_activity of NF-kappaB complex via CYBB
16720735 Diabetes mellitus, type II
Insulin resistance
3,141
28916 Angiotensin II increases_activity of PA-axis
28936 Angiotensin II decreases_activity of glucose utilization via a hyperreactive PA-axis
17595220 Diabetes mellitus, type II
Insulin resistance
3,819
38214 Angiotensin II increases_activity of angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure in pancreas
38219 Angiotensin II decreases_activity of insulin receptor signaling pathway via phosphatidylinositol 3-kinase in skeletal muscle, in cardiac muscle
38224 Angiotensin II decreases_activity of fat cell differentiation
16827595 Diabetes mellitus, type II
Insulin resistance
5,095
50091 Angiotensin II increases_expression of OLR1
16173915 Cardiovascular disease
Atherosclerosis
5,186
50781 Angiotensin II decreases_activity of vasodilation in cardiac aorta
20639222 Cardiovascular disease
6,401
60404 Angiotensin II increases_expression of SLC5A2 in type 2 diabetic patients
20546255 Diabetes mellitus, type II
Insulin resistance
6,456
61296 Metformin decreases_activity of Angiotensin II
22117616 Diabetes mellitus, type II
Cancer
Insulin resistance
6,515
61951 Metformin decreases_activity of Angiotensin II in cardiac muscle
21083698 Diabetes mellitus, type II
Insulin resistance
6,519
61998 Angiotensin II increases_quantity of Reactive oxygen species in aortic endothelial cells
62001 Angiotensin II increases_activity of NADPH oxidase complex in aortic endothelial cells
15931622 Diabetes mellitus, type II
Insulin resistance
Cardiomyopathy, diabetic
6,523
62375 Angiotensin II increases_activity of abnormal vascular endothelial cell physiology
18177481 Diabetes mellitus, type II
Insulin resistance
Cardiomyopathy, diabetic
6,900
68067 MTOR increases_quantity of Angiotensin II
27127460 Diabetes mellitus, type II
Insulin resistance
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