Search Results for "Olanzapine" - 152 interactions found in 30 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
1,273
8677 Olanzapine NOT decreases_activity of DNA hypermethylation of reelin promotor
20417248 Schizophrenia
1,699
12979 Olanzapine decreases_activity of Mitochondrial respiratory chain complex I
20980130 Schizophrenia
2,262
19310 Olanzapine decreases_activity of GSK3B
19325 Olanzapine increases_phosphorylation of GSK3B
16672106 Neurological
Schizophrenia
3,469
32288 Olanzapine decreases_expression of SLCO3A1
22507762 Parkinson disease
4,154
42833 Olanzapine increases_activity of binding density of CHRM3 in brain
42834 Olanzapine increases_activity of Obesity in animals treated with 0.5 mg/kg, 1.0 mg/kg and 2.0 mg/kg olanzapine
42835 Olanzapine increases_activity of increased food intake after 2.0 mg/kg olanzapine only
42836 Olanzapine increases_quantity of Ghrelin in blood plasma
42837 Olanzapine increases_quantity of CCK in blood plasma; in animals treated with 0.5 mg/kg and 2.0 mg/kg olanzapine
42838 Olanzapine decreases_quantity of Insulin in blood plasma
42839 Olanzapine decreases_quantity of Glucose in blood plasma; in animals treated with 0.5 mg/kg, 1.0 mg/kg and 2.0 mg/kg olanzapine
42854 Olanzapine NOT affects_activity of Obesity in animals treated with 1.0 mg/kg, 1.0 mg/kg and 2.0 mg/kg olanzapine
42855 Olanzapine increases_quantity of CCK in blood plasma; in animals treated with 1.0 mg/kg olanzapine
42856 Olanzapine NOT decreases_quantity of Glucose in blood plasma; in animals treated with 0.25 mg/kg olanzapine
21982116 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,155
42841 Olanzapine decreases_activity of CHRM1
42842 Olanzapine decreases_activity of CHRM2
42843 Olanzapine decreases_activity of CHRM3
42844 Olanzapine decreases_activity of CHRM4
42861 Olanzapine decreases_activity of HRH1
42863 Olanzapine decreases_activity of ADRA1A
10227113 Schizophrenia
4,157
42860 Olanzapine decreases_activity of Schizophrenia
42865 Olanzapine increases_activity of Obesity
42866 Olanzapine increases_activity of increased food intake
22695490 Schizophrenia
Obesity
4,159
42868 Olanzapine decreases_expression of HRH1 in hypothalamic arcuate nucleus and ventromedial hypothalamic nucleus
18358632 Schizophrenia
4,160
42879 Olanzapine increases_quantity of AMPK in hypothalamus; via blocking of hypothalamic H1 receptors
43777 Olanzapine increases_activity of Obesity
23640535 Schizophrenia
4,165
42906 CYP2D6 affects_quantity of Olanzapine
42907 CYP2D6 - c.A2637 deletion NOT affects_quantity of Olanzapine
11901361 Schizophrenia
Obesity
4,199
43098 Olanzapine NOT affects_activity of insulin secretion in non-diabetic adult psychiatric inpatients
23231880 Bipolar disorder
Diabetes mellitus, type II
Schizophrenia
Insulin resistance
Major depressive disorder
4,211
43162 Olanzapine increases_activity of Obesity
43165 Olanzapine increases_activity of Insulin resistance
18245179 Diabetes mellitus, type II
Schizophrenia
Obesity
Insulin resistance
4,235
43247 Olanzapine increases_activity of Obesity
43248 Olanzapine increases_activity of increased circulating leptin level
9989571 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,237
43267 Olanzapine increases_activity of Obesity
43269 Olanzapine increases_activity of increased circulating insulin level
43270 Olanzapine increases_activity of increased circulating leptin level
43272 Olanzapine increases_activity of hyperlipidemia
43273 Olanzapine increases_activity of Insulin resistance
11078035 Diabetes mellitus, type II
Schizophrenia
Obesity
Insulin resistance
4,239
43298 HTR2C rs3813929 affects_activity of Olanzapine concerning the weight-gain side-effect, the effective allele is C
15666332 Diabetes mellitus, type II
Schizophrenia
Obesity
Insulin resistance
4,243
43305 ADRA2A rs1800544 affects_activity of Olanzapine concerning the weight-gain side-effect, the effective allele is G
16583406 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,244
43316 HTR2A rs6313 affects_activity of Olanzapine concerning the weight-gain side-effect, the effective allele is T
43318 GNB3 rs5443 affects_activity of Olanzapine in schizophrenic patients treated with olanzapine, the effective allele is T
43321 HTR2C rs6318 affects_activity of Olanzapine concerning the weight-gain side-effect, the effective allele is G
43323 ADRB3 rs4994 affects_activity of Olanzapine concerning the weight-gain side-effect, the effective allele is C
19193342 Diabetes mellitus, type II
Schizophrenia
Obesity
Insulin resistance
4,253
43373 Olanzapine increases_activity of diabetic ketoacidosis
17259569 Bipolar disorder
Diabetes mellitus, type II
Insulin resistance
4,254
43377 Olanzapine increases_activity of hyperglycemia after long-term treatment
43378 Olanzapine increases_activity of hyperlipidemia after long-term treatment
43381 Olanzapine increases_activity of Diabetes mellitus, type II via hyperglycemia and hyperlipidemia, after long-term treatment
23090266 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,266
43628 Olanzapine decreases_activity of Alzheimer disease by up-regulation of TFAM, and down-regulation of PRNP
43629 Olanzapine increases_expression of TFAM
43630 Olanzapine decreases_expression of PRNP
43638 Olanzapine decreases_expression of THRA
43639 Olanzapine decreases_expression of PRNP
43640 Olanzapine increases_expression of IL1A
43641 Olanzapine increases_activity of Alzheimer disease by down-regulation of THRA and PRNP, and up-regulation of IL1A
21399480 Alzheimer disease
4,276
43738 Olanzapine decreases_activity of HTR2A
43745 Olanzapine decreases_activity of HTR2C
43746 Olanzapine decreases_activity of DRD1
43747 Olanzapine decreases_activity of DRD2
43748 Olanzapine decreases_activity of DRD3
43749 Olanzapine decreases_activity of DRD4
43750 Olanzapine decreases_activity of CHRM1
43751 Olanzapine decreases_activity of CHRM2
43752 Olanzapine decreases_activity of CHRM3
43753 Olanzapine decreases_activity of CHRM4
43754 Olanzapine decreases_activity of CHRM5
43755 Olanzapine decreases_activity of HRH1
43756 Olanzapine decreases_activity of ADRA1A
43757 CYP1A2 decreases_quantity of Olanzapine in liver
43758 CYP2D6 decreases_quantity of Olanzapine in liver
43759 CYP3A4 decreases_quantity of Olanzapine in liver
23559402 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,285
43973 Olanzapine increases_activity of increased susceptibility to weight gain
43974 Olanzapine increases_activity of increased liver weight
43975 Olanzapine increases_activity of decreased energy expenditure
43976 Olanzapine decreases_expression of SREBF1
45990 Olanzapine decreases_expression of FASN
45991 Olanzapine decreases_expression of ACLY
45992 Olanzapine increases_expression of GSK3B in liver
45993 Olanzapine increases_expression of GCK
45994 Olanzapine NOT affects_expression of CPT1A
45995 Olanzapine NOT affects_expression of PCK1
45996 Olanzapine NOT affects_expression of SLC2A1
45997 Olanzapine NOT affects_expression of SLC2A4
46100 Olanzapine increases_quantity of Glucose in blood plasma; in unfasted animals
46101 Olanzapine decreases_activity of glycogen biosynthetic process in liver; via increased GSK3B expression
46102 Olanzapine increases_quantity of Glutamine
46103 Olanzapine decreases_quantity of Leucine
46104 Olanzapine increases_quantity of Glutamate
46105 Olanzapine increases_activity of MTOR via phosphorylation at Ser248
46106 Olanzapine increases_activity of AMPK via phosphorylation
46107 Olanzapine increases_activity of canonical glycolysis in liver
46108 Olanzapine NOT affects_activity of Mitochondrial respiratory chain in liver
46109 Olanzapine increases_activity of impaired glucose tolerance
46110 Olanzapine increases_quantity of Triacylglycerol in liver, in blood plasma
23926289 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,682
46506 Olanzapine increases_activity of hyperglycemia after fasting, in healthy subjects
46507 Olanzapine decreases_quantity of Cortisol in blood serum; in healthy subjects
46508 Olanzapine decreases_quantity of Fatty acid in blood serum; after fasting, in healthy subjects
46509 Olanzapine increases_quantity of PRL in blood serum; in healthy subjects
24100786 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,683
46510 Olanzapine increases_activity of apoptotic process
46512 Olanzapine increases_activity of response to endoplasmic reticulum stress
46514 Olanzapine increases_activity of EIF2AK3
46522 Olanzapine decreases_activity of insulin secretion
46523 Olanzapine increases_quantity of Insulin in pancreatic beta cells
46524 Olanzapine increases_quantity of INS in pancreatic beta cells
23812432 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,684
46525 Olanzapine increases_activity of hyperglycemia in blood plasma; in wild-type and PMCH knock-out rats
46526 Olanzapine increases_quantity of Corticosterone in blood plasma; in wild-type and PMCH knock-out rats
46527 Olanzapine increases_activity of endogenous glucose production in wild-type and PMCH knock-out rats
46528 Melanin-concentrating hormone NOT affects_activity of Olanzapine in wild-type and PMCH knock-out rats if glucose metabolism is studied
23856185 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,686
46531 Olanzapine decreases_activity of Schizophrenia
46533 Olanzapine decreases_activity of Bipolar disorder
46535 Olanzapine increases_activity of Diabetes mellitus, type II
46536 Olanzapine increases_activity of Obesity
46537 Olanzapine increases_activity of hyperglycemia
46539 Olanzapine increases_activity of increased circulating insulin level after chronic olanzapine treatment
46541 Olanzapine increases_activity of Insulin resistance in liver
46543 Olanzapine decreases_activity of increased circulating insulin level after short-term olanzapine treatment
46562 Olanzapine decreases_activity of CHRM3
46578 Olanzapine increases_activity of decreased circulating insulin level in blood plasma; after fasting, independent of weight gain
24114586 Bipolar disorder
Diabetes mellitus, type II
Schizophrenia
Insulin resistance
5,053
49746 Olanzapine NOT affects_activity of MAPK3 in cortex and striatum
49748 Olanzapine NOT affects_activity of MAPK1 in cortex and striatum
23142770 Schizophrenia
5,084
49937 Olanzapine increases_activity of hyperglycemia after fasting
49939 Olanzapine increases_activity of Insulin resistance
22640703 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
5,086
49971 Olanzapine increases_activity of increased susceptibility to weight gain
49978 Olanzapine increases_quantity of white adipose tissue
49983 Olanzapine increases_activity of increased food intake
49990 Olanzapine decreases_quantity of brown adipose tissue
49993 Olanzapine decreases_expression of PRKAA2 in brown adipose tissue
50007 Olanzapine decreases_expression of UCP3 in brown adipose tissue
50008 Olanzapine decreases_expression of PPARGC1A in skeletal muscle
50013 Olanzapine decreases_expression of UCP2 in skeletal muscle
50015 Olanzapine increases_expression of PCK1 in liver
50017 Olanzapine decreases_expression of SLC2A4 in white adipose tissue, in brown adipose tissue, in skeletal muscle
50018 Olanzapine decreases_expression of SULT1A1 in brown adipose tissue
50021 Olanzapine decreases_expression of PKM2 in brown adipose tissue
50026 Olanzapine decreases_expression of PCK2 in brown adipose tissue
50027 Olanzapine decreases_expression of SREBF1 in white adipose tissue
50030 Olanzapine decreases_expression of UCP1 in brown adipose tissue
50037 Olanzapine decreases_expression of RETN in brown adipose tissue
50039 Olanzapine decreases_expression of FASN in brown adipose tissue
50042 Olanzapine decreases_expression of GPAM in brown adipose tissue
50044 Olanzapine decreases_expression of INSIG2 in brown adipose tissue
50047 Olanzapine decreases_expression of NR1H3 in brown adipose tissue
50050 Olanzapine decreases_expression of ACADVL in brown adipose tissue
50053 Olanzapine decreases_expression of CEBPA in brown adipose tissue, in liver
50056 Olanzapine decreases_expression of PPARG in brown adipose tissue
50058 Olanzapine increases_expression of INSIG2 in liver
50060 Olanzapine decreases_expression of HMGCR in liver
50063 Olanzapine decreases_expression of LDLR in skeletal muscle
50065 Olanzapine increases_expression of SCD in white adipose tissue
50066 Olanzapine decreases_expression of APOE in white adipose tissue
24667776 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
5,093
50078 Olanzapine increases_activity of JAK2 in frontal cortex
19304867 Neurological
-->