Search Results for "Curcumin" - 66 interactions found in 12 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
595
3133 Curcumin NOT affects_activity of Insulin receptor
3134 Curcumin NOT decreases_activity of Alpha glucosidase
3143 Curcumin NOT decreases_activity of DPP4
3144 Curcumin affects_activity of PCK1 in H4IIE rat hepatoma and Hep3B human hepatoma cells
3147 Curcumin increases_phosphorylation of AMPK in H4IIE and Hep3B cells
3148 Curcumin increases_phosphorylation of ACACB in H4IIE and Hep3B cells
12849 Curcumin affects_activity of G6PC in H4IIE rat hepatoma and Hep3B human hepatoma cells
19665995 Diabetes mellitus, type II
Insulin resistance
737
4139 Curcumin decreases_activity of neuron death induced by 6-OHDA
4177 Curcumin decreases_activity of 6-OHDA
18665912 Parkinson disease
908
5543 Curcumin interacts (colocalizes) with Amyloid beta peptide and inhibits Abeta aggregation
5544 Curcumin decreases_quantity of amyloid beta deposits
5548 Curcumin decreases_quantity of Oxidized protein
5549 Curcumin decreases_quantity of IL1B in brain; of Tg2576 mouse
5551 Curcumin decreases_activity of inflammatory response
5557 Curcumin increases_activity of response to oxidative stress
5562 Curcumin increases_activity of neuroprotection
80156 Curcumin decreases_activity of amyloid fibril formation
80157 Curcumin decreases_quantity of Amyloid beta peptide (oligomer)
19191039 Alzheimer disease
Parkinson disease
Atherosclerosis
1,107
7571 Curcumin decreases_activity of lipid peroxidation
7574 Curcumin decreases_activity of Reactive oxygen species
7577 Curcumin decreases_activity of cyclooxygenase pathway
7579 Curcumin decreases_activity of NF-kappaB complex Curcumin inhibits cyclooxygenase enzymes and reduces the activation of nuclear transcription factor NF-kappaB.
20462385 Alzheimer disease
Dementia
1,518
10744 Curcumin decreases_activity of Diabetes mellitus, type II in mouse models of obesity-related diabetes
10746 Curcumin decreases_quantity of macrophage in perigonadal white adipose tissue; in mouse models of obesity-related diabetes
10747 Curcumin decreases_expression of EMR1 in perigonadal white adipose tissue; in mouse models of obesity-related diabetes
10748 Curcumin increases_expression of FOXO1 in perigonadal white adipose tissue; in mouse models of obesity-related diabetes
10749 Curcumin increases_expression of ADIPOQ in perigonadal white adipose tissue; in mouse models of obesity-related diabetes
10750 Curcumin decreases_expression of TNF in liver; in ob/ob mice
10751 Curcumin decreases_expression of SOCS3 in liver; in ob/ob mice
10752 Curcumin decreases_expression of CCL2 in liver; in ob/ob mice
10753 Curcumin decreases_expression of CCR2 in liver; in ob/ob mice
10754 Curcumin decreases_activity of inflammatory response in liver
18403477 Diabetes mellitus, type II
Obesity
Insulin resistance
1,592
11574 Curcumin decreases_expression of IL1B
11575 Curcumin decreases_expression of STAT3
11576 Curcumin decreases_expression of ABCB1
11577 Curcumin decreases_expression of SCD
11611 Curcumin decreases_expression of PTGS1 in inflamed cells
11612 Curcumin decreases_expression of CYP1A1 in inflamed cells
11613 Curcumin decreases_expression of CYP3A4 in inflamed cells
20816778 Diabetes mellitus, type II
Insulin resistance
1,820
13649 Curcumin decreases_expression of IRAK2
13650 Curcumin decreases_expression of mir-146a
13652 Curcumin increases_expression of IRAK1
20937840 Alzheimer disease
1,949
15066 Curcumin decreases_activity of NF-kappaB complex in adipose tissue
15069 Curcumin decreases_expression of TNF in adipose tissue; via inhibition of NF-kappaB activation
15072 Curcumin decreases_expression of IL1B in adipose tissue; via inhibition of NF-kappaB activation
15076 Curcumin decreases_expression of IL6 in adipose tissue; via inhibition of NF-kappaB activation
15078 Curcumin decreases_expression of PTGS2 in adipose tissue; via inhibition of NF-kappaB activation
15081 Curcumin decreases_quantity of Prostaglandin E2 in adipose tissue; via inhibition of NF-kappaB activation
15083 Curcumin decreases_activity of I-kappaB kinase/NF-kappaB signaling in adipose tissue
18549505 Diabetes mellitus, type II
Obesity
Insulin resistance
3,238
29898 Curcumin affects_activity of inflammatory response
29900 Curcumin affects_activity of response to oxidative stress
29902 Curcumin affects_activity of amyloidosis
15974909 Alzheimer disease
3,870
38971 Curcumin decreases_activity of PAK1
23162743 Alzheimer disease
Huntington disease
5,265
51316 Curcumin decreases_expression of CYP1A1 in MCF-7 breast cancer cells, in Hep3B hepatic cancer cells; if expression was induced by dioxin
51320 Curcumin decreases_expression of CYP1B1 in MCF-7 breast cancer cells, in Hep3B hepatic cancer cells; if expression was induced by dioxin
51322 Curcumin decreases_quantity of ARNT in Hep3B hepatic cancer cells
51328 Curcumin decreases_quantity of AHR in Hep3B hepatic cancer cells
51331 Curcumin decreases_activity of AHR in Hep3B hepatic cancer cells; via inhibition of dioxin-induced translocation into the nucleus
51333 Curcumin decreases_activity of ARNT in Hep3B hepatic cancer cells; via inhibition of dioxin-induced translocation into the nucleus
51334 Curcumin increases_activity of proteasome-mediated ubiquitin-dependent protein catabolic process in MCF-7 breast cancer cells, in Hep3B hepatic cancer cells; via increased oxidative stress
51342 Curcumin increases_activity of response to oxidative stress in MCF-7 breast cancer cells, in Hep3B hepatic cancer cells
51344 Curcumin increases_quantity of Reactive oxygen species in MCF-7 breast cancer cells, in Hep3B hepatic cancer cells
51345 Curcumin decreases_activity of 2,3,7,8-Tetrachlorodibenzodioxin in MCF-7 breast cancer cells, in Hep3B hepatic cancer cells
51350 Curcumin decreases_activity of tumorigenesis in PNT2 prostate cells, in HEK293 cells; if induced by dioxin
19018768 Diabetes mellitus, type II
Cancer
Insulin resistance
6,834
66528 Curcumin increases_expression of CISD2 after spinal cord injury
66529 Curcumin decreases_activity of inflammatory response after spinal cord injury
26387034 Diabetes mellitus, type II
Insulin resistance
Wolfram syndrome 2
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