Search Results for "Atorvastatin" - 48 interactions found in 9 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
703
3948 Atorvastatin decreases_activity of VLDL secretion in insulin-resistant Syrian golden hamsters
3949 Atorvastatin increases_activity of increased insulin sensitivity
11597827 Diabetes mellitus, type II
Insulin resistance
1,572
11256 Atorvastatin decreases_quantity of Cholesterol in blood
11257 Atorvastatin decreases_quantity of LDL in blood
11258 Atorvastatin increases_quantity of HDL in blood
11259 Atorvastatin decreases_quantity of NF-kappaB complex in nucleus
11260 Atorvastatin increases_quantity of NF-kappaB complex in cytoplasm
11264 Atorvastatin decreases_quantity of TNF in lipopolysaccharide-activated monocytes
11265 Atorvastatin decreases_activity of inflammatory response in type 2 diabetics
13618 Atorvastatin decreases_activity of atherosclerotic lesions in type 2 diabetics
20134099 Diabetes mellitus, type II
Insulin resistance
Atherosclerosis
2,249
19227 Atorvastatin decreases_activity of neurodegeneration neuroprotection against cell degeneration induced by Abeta (1-40)
19228 Atorvastatin decreases_activity of inflammatory response
19229 Atorvastatin decreases_activity of response to oxidative stress
19230 Atorvastatin increases_expression of Glutamatergic transporter
19233 Atorvastatin NOT affects_quantity of Amyloid beta peptide
19236 Atorvastatin decreases_quantity of BACE1
19237 Atorvastatin decreases_activity of lipid peroxidation
19252 Atorvastatin decreases_activity of protein oxidation
19253 Atorvastatin decreases_activity of protein nitrosylation
19254 Atorvastatin increases_quantity of Glutathione cholesterol- and Abeta-independent and specific for brain
19256 Atorvastatin decreases_quantity of Ubichinon-10 (side effects of long-term statin treatment)
19259 Atorvastatin increases_activity of abnormal aerobic energy metabolism in heart, skeletal muscle, and liver; (as side effect of long-term statin treatment)
19270 Atorvastatin NOT decreases_activity of cognitive impairment (LEADe study)
19280 Atorvastatin decreases_activity of cognitive impairment (ADCLT trial)
21536132 Alzheimer disease
Dementia
2,269
19373 Atorvastatin NOT increases_activity of memory in aged dogs
19388 Atorvastatin decreases_quantity of LDL in aged dogs
19389 Atorvastatin decreases_quantity of HDL in aged dogs
19390 Atorvastatin decreases_quantity of Triacylglycerol in aged dogs
19391 Atorvastatin decreases_quantity of Cholesterol in aged dogs
19405 Atorvastatin affects_quantity of Omega-6 fatty acid CHEBI: 36009 omega-6 fatty acid
19407 Atorvastatin affects_quantity of Omega-3 fatty acid CHEBI: 25681 omega-3 fatty acid
19411 Atorvastatin NOT affects_quantity of APP
20847439 Alzheimer disease
2,371
20808 Atorvastatin decreases_activity of lipid peroxidation in parietal cortex of aged beagles
20810 Atorvastatin decreases_activity of protein oxidation in parietal cortex of aged beagles
20812 Atorvastatin decreases_activity of protein nitrosylation in parietal cortex of aged beagles
20813 Atorvastatin increases_quantity of Glutathione in parietal cortex of aged beagles
20814 Atorvastatin affects_activity of cholesterol catabolic process in cortex; formation of cholesterol oxidation products was affected
21193043 Alzheimer disease
3,917
39760 Atorvastatin decreases_activity of LDL in blood plasma
39761 Atorvastatin decreases_quantity of APOB in blood plasma
39762 Atorvastatin increases_activity of increased circulating insulin level in blood plasma; after fasting
39770 Atorvastatin increases_quantity of Glycated hemoglobin in blood plasma
39771 Atorvastatin increases_activity of decreased insulin sensitivity
39772 Atorvastatin increases_activity of Insulin resistance
20298928 Diabetes mellitus, type II
Insulin resistance
4,407
44779 Atorvastatin interacts (colocalizes) with HMGCR
44786 Atorvastatin decreases_activity of HMGCR
23703578 Metabolic
4,986
49264 Atorvastatin decreases_expression of OLR1
49265 Atorvastatin decreases_quantity of OLR1
Cardiovascular disease
Atherosclerosis
5,451
53202 Atorvastatin decreases_phosphorylation of AKT1 insulin- and cytostatic drug-induced Akt phosphorylation
17121917 Metabolic
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