|
20
|
| 55 |
response to hypoxia
|
|
decreases_quantity of
|
NRP1
|
|
| 56 |
response to hypoxia
|
NOT |
decreases_quantity of
|
NRP2
|
|
|
18708346
|
Amyotrophic lateral sclerosis
|
|
289
|
| 1151 |
response to hypoxia
|
|
increases_expression of
|
ANG
|
exposed to atmospheric hypoxia of 10, 3 and 1% O(2) for 24 h
|
| 1155 |
response to hypoxia
|
|
increases_expression of
|
VEGFA
|
exposed to atmospheric hypoxia of 10, 3 and 1% O(2) for 24 h
|
| 1170 |
response to hypoxia
|
|
increases_expression of
|
HIF1A
|
already detectable after 4 h at 1% O(2)
|
|
19444281
|
Amyotrophic lateral sclerosis
|
|
736
|
| 4310 |
response to hypoxia
|
|
increases_activity of
|
LPIN1
|
in liver
|
|
18023282
|
Diabetes mellitus, type II
Obesity
Lipodystrophy
Insulin resistance
Fatty liver disease, nonalcoholic
Majeed syndrome
|
|
858
|
| 5099 |
response to hypoxia
|
NOT |
affects_expression of
|
VEGFB
|
|
|
18923022
|
Amyotrophic lateral sclerosis
|
|
1,346
|
| 9179 |
response to hypoxia
|
|
increases_quantity of
|
NADH
|
|
| 9181 |
response to hypoxia
|
|
increases_activity of
|
increased metastatic potential
|
|
|
16740659
|
Disease-related-protein CtBP
|
|
1,531
|
| 10915 |
response to hypoxia
|
|
increases_expression of
|
TH
|
|
|
20649842
|
Parkinson disease
|
|
1,532
|
| 10918 |
response to hypoxia
|
|
increases_activity of
|
HIF1A
|
|
| 10920 |
response to hypoxia
|
|
decreases_activity of
|
HPH
|
|
|
20649842
|
Parkinson disease
|
|
1,822
|
| 13667 |
DDIT4
|
|
affects_activity of
|
response to hypoxia
|
|
|
21258409
|
Neurological
|
|
2,814
|
| 26038 |
response to hypoxia
|
|
decreases_activity of
|
MTOR
|
|
|
21912508
|
Diabetes mellitus, type II
Cancer
Insulin resistance
Metabolic syndrome
|
|
3,200
|
| 29484 |
response to hypoxia
|
|
increases_activity of
|
cerebral insulin suppression
|
|
|
21660101
|
Diabetes mellitus, type II
Insulin resistance
|
|
3,470
|
| 32289 |
response to hypoxia
|
|
increases_expression of
|
SLC25A37
|
|
| 32290 |
response to hypoxia
|
|
increases_expression of
|
TGFB1
|
|
| 32427 |
response to hypoxia
|
|
increases_quantity of
|
HIF1A
|
|
|
19187226
|
Hematological
|
|
3,495
|
| 32454 |
response to hypoxia
|
|
decreases_activity of
|
AKT1
|
|
| 32460 |
response to hypoxia
|
|
decreases_activity of
|
PIK3CA
|
|
|
12764143
|
Hepatocellular carcinoma
|
|
3,542
|
| 32951 |
response to hypoxia
|
|
increases_expression of
|
HIF1A
|
|
|
7539918
|
Neurological
|
|
3,795
|
| 37685 |
response to hypoxia
|
|
increases_activity of
|
AMPK
|
|
| 37688 |
response to hypoxia
|
|
increases_expression of
|
DDIT4
|
|
|
18765678
|
Diabetes mellitus, type II
Insulin resistance
|
|
4,051
|
| 41800 |
response to hypoxia
|
|
increases_expression of
|
EWSR1
|
|
|
20442286
|
Ewing sarcoma
|
|
4,109
|
| 42398 |
response to hypoxia
|
|
increases_expression of
|
LEP
|
|
|
12215445
|
Diabetes mellitus, type II
Insulin resistance
|
|
4,139
|
| 42706 |
response to hypoxia
|
|
increases_expression of
|
SLC2A1
|
in pancreas, in pancreatic islet
|
| 42707 |
response to hypoxia
|
NOT |
increases_expression of
|
SLC2A2
|
in pancreas, in pancreatic islet
|
|
20440072
|
Diabetes mellitus, type II
Insulin resistance
|
|
4,142
|
| 42735 |
high-fat high-sucrose diet
|
|
increases_activity of
|
response to hypoxia
|
in liver
|
| 42741 |
response to hypoxia
|
|
increases_expression of
|
HIF1A
|
in liver
|
|
22051049
|
Diabetes mellitus, type II
Insulin resistance
|
|
4,751
|
| 47041 |
response to hypoxia
|
|
decreases_quantity of
|
NO
|
|
| 47042 |
response to hypoxia
|
|
decreases_expression of
|
NOS3
|
|
|
7526714
|
Metabolic
Cardiovascular disease
|
|
5,241
|
| 51107 |
SIRT1
|
|
affects_activity of
|
response to hypoxia
|
|
|
20005308
|
Diabetes mellitus, type II
Insulin resistance
|
|
5,299
|
| 51799 |
response to hypoxia
|
|
increases_expression of
|
VEGFA
|
in skeletal muscle
|
| 51864 |
response to hypoxia
|
|
increases_expression of
|
SLC2A1
|
in skeletal muscle
|
| 51865 |
response to hypoxia
|
|
increases_expression of
|
PDK1
|
in skeletal muscle
|
| 51866 |
response to hypoxia
|
|
increases_expression of
|
NT-PPARGC1A-a
|
in skeletal muscle
|
| 51867 |
response to hypoxia
|
|
increases_expression of
|
NT-PPARGC1A-b
|
in skeletal muscle
|
| 51868 |
response to hypoxia
|
NOT |
affects_expression of
|
PPARGC1A
|
in skeletal muscle
|
|
24505137
|
Diabetes mellitus, type II
Insulin resistance
|
|
5,314
|
| 52490 |
response to hypoxia
|
|
increases_expression of
|
PPARGC1A
|
|
| 52492 |
response to hypoxia
|
|
increases_expression of
|
VEGF
|
in skeletal muscle; via PPARGC1A
|
|
18288196
|
Diabetes mellitus, type II
Insulin resistance
|
|
5,879
|
| 55546 |
response to hypoxia
|
|
increases_activity of
|
pulmonary hypertension
|
|
| 55548 |
response to hypoxia
|
|
increases_phosphorylation of
|
SMAD1
|
thereby increasing SMAD activity
|
| 55549 |
response to hypoxia
|
|
increases_phosphorylation of
|
SMAD5
|
thereby increasing SMAD activity
|
| 55550 |
response to hypoxia
|
|
increases_phosphorylation of
|
SMAD9
|
thereby increasing SMAD activity
|
| 55551 |
response to hypoxia
|
|
decreases_phosphorylation of
|
p38 MAPK
|
|
| 55554 |
response to hypoxia
|
|
increases_activity of
|
BMPR2
|
|
| 55556 |
response to hypoxia
|
|
increases_activity of
|
BMP signaling pathway
|
|
| 55606 |
response to hypoxia
|
|
increases_quantity of
|
NOS3
|
|
| 55607 |
response to hypoxia
|
|
increases_quantity of
|
NOS2
|
|
|
18024717
|
Pulmonary hypertension
Lung disease
|
|
5,909
|
| 55794 |
response to hypoxia
|
|
increases_expression of
|
EDN1
|
|
|
25403488
|
Osteoarthritis
Sickle cell anemia
|
|
5,910
|
| 55860 |
response to hypoxia
|
|
decreases_expression of
|
HAMP
|
|
|
|
Diabetes mellitus, type II
Insulin resistance
Hemochromatosis, type 1
|
|
6,123
|
| 57342 |
response to hypoxia
|
|
decreases_expression of
|
PPARGC1A
|
|
|
26119730
|
Renal cell carcinoma, clear cell
|
|
6,129
|
| 57350 |
response to hypoxia
|
|
decreases_expression of
|
PPARG2
|
|
| 57406 |
response to hypoxia
|
|
increases_expression of
|
DEC1
|
|
|
11879638
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,130
|
| 57351 |
response to hypoxia
|
|
increases_expression of
|
HIF1A
|
|
| 57416 |
response to hypoxia
|
|
decreases_expression of
|
MAFA
|
|
| 57417 |
response to hypoxia
|
|
decreases_expression of
|
PDX1
|
|
| 57418 |
response to hypoxia
|
|
decreases_expression of
|
SLC2A2
|
|
| 57419 |
response to hypoxia
|
|
decreases_expression of
|
NDUFA5
|
|
| 57420 |
response to hypoxia
|
|
decreases_expression of
|
KCNJ11
|
|
| 57421 |
response to hypoxia
|
|
decreases_expression of
|
INS
|
|
| 57422 |
response to hypoxia
|
|
decreases_expression of
|
WFS1
|
|
| 57423 |
response to hypoxia
|
|
decreases_expression of
|
FOXA2
|
|
| 57424 |
response to hypoxia
|
|
decreases_expression of
|
NEUROD1
|
|
| 57425 |
response to hypoxia
|
|
affects_activity of
|
insulin secretion
|
|
| 57426 |
response to hypoxia
|
|
increases_activity of
|
apoptotic process
|
|
| 57427 |
response to hypoxia
|
|
increases_expression of
|
PDK1
|
via HIF1A
|
| 57428 |
response to hypoxia
|
|
increases_expression of
|
LDHA
|
via HIF1A
|
| 57429 |
response to hypoxia
|
|
decreases_expression of
|
HNF1A
|
|
| 57430 |
response to hypoxia
|
|
decreases_expression of
|
NKX2-2
|
|
| 57431 |
response to hypoxia
|
|
decreases_expression of
|
HNF4A
|
|
| 57432 |
response to hypoxia
|
|
decreases_expression of
|
GLP1R
|
|
| 57433 |
response to hypoxia
|
|
decreases_expression of
|
ABCC8
|
|
| 57434 |
response to hypoxia
|
|
decreases_expression of
|
IRS1
|
|
| 57435 |
response to hypoxia
|
|
increases_expression of
|
IAPP
|
|
| 57436 |
response to hypoxia
|
|
increases_expression of
|
IGF1R
|
|
| 57437 |
response to hypoxia
|
|
increases_expression of
|
INSR
|
|
| 57438 |
response to hypoxia
|
|
increases_expression of
|
GIPR
|
|
|
25503986
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,145
|
| 57483 |
response to hypoxia
|
|
decreases_expression of
|
PRKCE
|
via epigenetic repression
|
| 57526 |
response to hypoxia
|
|
increases_quantity of
|
HIF1A
|
in nucleus
|
| 57527 |
response to hypoxia
|
|
increases_quantity of
|
Reactive oxygen species
|
|
| 57530 |
response to hypoxia
|
|
affects_activity of
|
regulation of gene expression, epigenetic
|
|
|
22139554
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,362
|
| 59785 |
response to hypoxia
|
|
decreases_quantity of
|
Pyruvate
|
in mitochondrion
|
| 59786 |
response to hypoxia
|
|
increases_activity of
|
HIF1A
|
|
| 59789 |
response to hypoxia
|
NOT |
decreases_activity of
|
anaplerosis
|
|
| 59791 |
response to hypoxia
|
|
increases_transport of
|
Glutamine
|
into the cell
|
| 59792 |
response to hypoxia
|
|
increases_activity of
|
reductive glutamine metabolism
|
|
|
22212478
|
Diabetes mellitus, type II
Cancer
Insulin resistance
|
CIDeR