Search Results for "Resveratrol" - 125 interactions found in 25 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
9
40 Resveratrol increases_activity of SIRT1
41 Resveratrol decreases_activity of RELA
19008341 Diabetes mellitus, type I
12
48 Resveratrol increases_activity of insulin secretion in cytokine treated cells
19008341 Diabetes mellitus, type I
39
91 Resveratrol increases_activity of SIRT1
99 Resveratrol decreases_activity of EP300
15152190 Diabetes mellitus, type I
824
5131 Resveratrol increases_activity of SIRT
5132 Resveratrol decreases_acetylation of PPARGC1A in high-fat fed mice
5133 Resveratrol increases_activity of PPARGC1A in high-fat fed mice
5134 Resveratrol decreases_activity of increased susceptibility to weight gain in high-fat fed mice
5135 Resveratrol decreases_activity of Insulin resistance in high-fat fed mice
19770177 Diabetes mellitus, type II
Obesity
Insulin resistance
908
5512 Resveratrol increases_activity of neuroprotection
5514 Resveratrol decreases_activity of inflammatory response
5515 Resveratrol decreases_activity of hyperlipidemia
5516 Resveratrol decreases_activity of atherosclerotic lesions
5517 Resveratrol decreases_activity of fever generation
5519 Resveratrol decreases_quantity of amyloid beta deposits
5528 Resveratrol decreases_quantity of Amyloid beta peptide via a mechanism that involves the proteasome
5531 Resveratrol decreases_expression of PTGS2
5536 Resveratrol decreases_expression of NOS2
5744 Resveratrol affects_activity of Alzheimer disease in Tg2576 mouse
19191039 Alzheimer disease
Parkinson disease
Atherosclerosis
1,002
6233 Resveratrol NOT increases_expression of NQO1
17982879 Parkinson disease
1,023
6420 Resveratrol increases_activity of SIRT1
6421 Resveratrol decreases_activity of NF-kappaB complex induced by amyloid beta peptide
106877 Resveratrol decreases_activity of positive regulation of NF-kappaB transcription factor activity induced by amyloid beta peptide
16183991 Alzheimer disease
1,107
7584 Resveratrol increases_expression of HMOX1
7585 Resveratrol affects_activity of response to oxidative stress
20819 Resveratrol decreases_activity of response to oxidative stress
20462385 Alzheimer disease
Dementia
1,513
10707 Resveratrol increases_activity of increased insulin sensitivity in mice on high-calorie diet
10710 Resveratrol decreases_quantity of IGF1 in mice on high-calorie diet
10711 Resveratrol increases_activity of AMPK in mice on high-calorie diet
10714 Resveratrol increases_activity of PPARGC1A in mice on high-calorie diet
10716 Resveratrol increases_quantity of mitochondrion in mice on high-calorie diet
10724 Resveratrol decreases_activity of insulin receptor signaling pathway in mice on high-calorie diet
10727 Resveratrol decreases_activity of TOR signaling in mice on high-calorie diet
10732 Resveratrol decreases_activity of oxidative phosphorylation in mice on high-calorie diet
10734 Resveratrol decreases_activity of electron transport chain in mice on high-calorie diet
10736 Resveratrol decreases_activity of canonical glycolysis in mice on high-calorie diet
10737 Resveratrol increases_activity of STAT3 signaling pathway in mice on high-calorie diet
17086191 Diabetes mellitus, type II
Insulin resistance
1,581
11377 Resveratrol increases_activity of NF-kappaB complex in intestine
11385 Resveratrol increases_quantity of CXCL8 in intestine
18377686 Diabetes mellitus, type II
Insulin resistance
1,592
11553 Resveratrol decreases_expression of IL1B
11585 Resveratrol decreases_expression of IL6 in inflamed cells
11586 Resveratrol decreases_expression of PTGS1 in inflamed cells
11587 Resveratrol decreases_expression of OCLN in inflamed cells
20816778 Diabetes mellitus, type II
Insulin resistance
1,949
15068 Resveratrol decreases_activity of NF-kappaB complex in adipose tissue
15070 Resveratrol decreases_expression of TNF in adipose tissue; via inhibition of NF-kappaB activation
15074 Resveratrol decreases_expression of IL1B in adipose tissue; via inhibition of NF-kappaB activation
15077 Resveratrol decreases_expression of IL6 in adipose tissue; via inhibition of NF-kappaB activation
15079 Resveratrol decreases_expression of PTGS2 in adipose tissue; via inhibition of NF-kappaB activation
15082 Resveratrol decreases_quantity of Prostaglandin E2 in adipose tissue; via inhibition of NF-kappaB activation
15086 Resveratrol decreases_activity of I-kappaB kinase/NF-kappaB signaling in adipose tissue
18549505 Diabetes mellitus, type II
Obesity
Insulin resistance
2,786
25746 Resveratrol increases_quantity of Glucagon-like peptide 1 in blood, in intestine
25755 Resveratrol increases_quantity of Insulin in blood
25756 Resveratrol decreases_activity of impaired glucose tolerance in blood
25757 Resveratrol decreases_expression of GCG in intestine
25758 Resveratrol affects_activity of glucose homeostasis via GLP1R
25760 Resveratrol affects_activity of gut flora in intestine, in cecum
25761 Resveratrol decreases_activity of inflammatory response
25762 Resveratrol increases_expression of IL10 in colon, in liver, in muscle, in brain
25763 Resveratrol increases_expression of TGFB1 in colon, in liver, in muscle
25764 Resveratrol decreases_expression of TNF in colon, in liver, in muscle
25765 Resveratrol NOT affects_expression of GCG in brain
25766 Resveratrol decreases_expression of SERPINE1 in brain
25767 Resveratrol decreases_activity of Diabetes mellitus, type II via GLP-1 and GLP1R
21673955 Diabetes mellitus, type II
Insulin resistance
5,129
50334 Resveratrol affects_quantity of Hydroxyl radical via NQO2
50335 Resveratrol affects_activity of NQO2
21762045 Diabetes mellitus, type II
Insulin resistance
5,152
50388 Resveratrol decreases_activity of albuminuria in db/db mice
50390 Resveratrol decreases_activity of expanded mesangial matrix in kidney; in db/db mice
50391 Resveratrol decreases_activity of inflammatory response in kidney; in db/db mice
50393 Resveratrol decreases_quantity of Collagen IV in kidney; in db/db mice
50398 Resveratrol decreases_quantity of Fatty acid in kidney; in db/db mice
50400 Resveratrol decreases_quantity of Triacylglycerol in kidney; in db/db mice
50401 Resveratrol increases_activity of AMPK in kidney; in db/db mice, via phosphorylation at Thr172 of AMPK alpha chain
50404 Resveratrol increases_activity of SIRT1 in kidney; in db/db mice
50405 Resveratrol increases_activity of PPARGC1A in kidney; in db/db mice, via increased acetylated Lys-PGC-1alpha levels
50408 Resveratrol increases_activity of SREBF1 in kidney; in db/db mice
50409 Resveratrol decreases_activity of Phosphatidylinositol 3-kinase in kidney; in db/db mice
50411 Resveratrol decreases_activity of AKT1 in kidney; in db/db mice, via decreased phosphorylation at Ser473
50412 Resveratrol decreases_activity of response to oxidative stress in kidney; in db/db mice
50414 Resveratrol decreases_quantity of 8-Hydroxy-deoxyguanosine in kidney, in urine; in db/db mice
50416 Resveratrol decreases_quantity of 8-Isoprostane in urine; in db/db mice
50418 Resveratrol decreases_phosphorylation of FOXO3a in kidney; in db/db mice, at Ser253
50426 Resveratrol increases_quantity of BCL2 in kidney; in db/db mice
50428 Resveratrol decreases_quantity of BAX in kidney; in db/db mice
50430 Resveratrol increases_quantity of SOD1 in kidney; in db/db mice
50431 Resveratrol increases_quantity of SOD2 in kidney; in db/db mice
50432 Resveratrol decreases_activity of Nephropathy, diabetic in db/db mice
23090186 Diabetes mellitus, type II
Insulin resistance
Nephropathy, diabetic
5,160
50474 Resveratrol affects_quantity of AKT1-NQO2 complex
50475 AKT1 interacts (colocalizes) with Resveratrol
50476 Resveratrol NOT affects_expression of NQO2
50478 Resveratrol decreases_activity of AKT1
24968355 Diabetes mellitus, type II
Insulin resistance
5,161
50480 Resveratrol decreases_activity of NQO2
15350128 Diabetes mellitus, type II
Insulin resistance
5,241
51108 Resveratrol increases_activity of SIRT1
51110 Resveratrol increases_activity of PPARGC1A via SIRT1 activation
20005308 Diabetes mellitus, type II
Insulin resistance
5,264
51311 Resveratrol decreases_expression of CYP1A1 in MCF-7 breast cancer cells, in HepG2 hepatic cancer cells; if expression was induced by dioxin
51312 Resveratrol decreases_expression of CYP1B1 in MCF-7 breast cancer cells; if expression was induced by dioxin
51313 Resveratrol decreases_expression of CYP1A2 in MCF-7 breast cancer cells, in HepG2 hepatic cancer cells; if expression was induced by dioxin
51314 Resveratrol decreases_activity of AHR via decreased recruitment to xenobiotic response elements
51315 Resveratrol decreases_activity of ARNT via decreased recruitment to xenobiotic response elements
19376845 Diabetes mellitus, type II
Cancer
Insulin resistance
6,140
57466 Resveratrol decreases_expression of ABCB1
57508 Resveratrol increases_quantity of Rhodamine 123 via decreased export
57509 Resveratrol decreases_activity of drug export
57510 Resveratrol decreases_activity of NF-kappaB complex
57511 Resveratrol increases_activity of NFKBIA via decreased phosphorylation
57512 Resveratrol decreases_activity of RELA via decreased translocation into the nucleus
57513 Resveratrol increases_activity of AMPK
57514 Resveratrol decreases_phosphorylation of CREB1
26124005 Colorectal cancer
Diabetes mellitus, type II
Insulin resistance
6,275
58636 Resveratrol decreases_expression of AKT1 in U251 glioma cells
58700 Resveratrol increases_activity of CASP3 in U251 glioma cells
58704 Resveratrol increases_activity of increased lactate dehydrogenase release in U251 glioma cells
58711 Resveratrol decreases_phosphorylation of RPS6 in U251 glioma cells
58713 Resveratrol decreases_expression of CCND1 in U251 glioma cells
58714 Resveratrol decreases_activity of phosphatidylinositol 3-kinase signaling in U251 glioma cells
19827268 Glioblastoma
6,302
60219 Resveratrol increases_activity of SIRT1 resulting in an inhibition of cell growth by inducing cell cycle arrest.
26378621 Breast cancer
6,387
61652 Resveratrol increases_activity of SIRT1 depending on a functional AMPK.
61672 Resveratrol increases_activity of autophagy in human cultured cells; in a Sirt1-dependent and Sirt1-independent way.
25955819 Metabolic
6,542
63631 Resveratrol increases_activity of AMPK by increasing intracellular Ca2+ levels and by promoting AMPK phosphorylation at Thr-172 by CaMKKbeta.
63755 Resveratrol increases_quantity of Ca2+ hereby activating AMPK via phosphorylation by CaMKKbeta.
63756 Resveratrol increases_phosphorylation of AMPK at Thr-172 by CaMKKbeta, hereby activating AMPK.
63757 Resveratrol decreases_activity of MTOR by increasing intracellular Ca2+ levels and by promoting AMPK phosphorylation at Thr-172 by CaMKKbeta.
63758 Resveratrol decreases_quantity of Amyloid beta peptide in vitro; via intracellular degradation of Abeta by the lysosomal system.
63759 Resveratrol increases_activity of autophagy via activating AMPK.
63760 Resveratrol increases_activity of CAMKK2 by increasing intracellular Ca2+ levels.
63857 Melatonin increases_activity of Resveratrol
22367557 Alzheimer disease
6,831
66480 Resveratrol decreases_activity of CISD2
23717386 Diabetes mellitus, type II
Insulin resistance
Wolfram syndrome 2
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