Search Results for "Lovastatin" - 24 interactions found in 6 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
4,327
44287 Lovastatin decreases_activity of Amyloid beta peptide (42) in differentiated SK-NSH cells; by preventing apoptosis
44290 Lovastatin decreases_activity of neuron apoptotic process in differentiated SK-NSH cells
44291 Lovastatin decreases_quantity of GSK3B -phos (activated)
44292 Lovastatin increases_transport of CTNNB1 (increased nuclear translocation of beta-catenin)
44293 Lovastatin increases_transport of TCF3 (increased nuclear translocation of TCF-3)
44294 Lovastatin increases_transport of LEF1 (increased nuclear translocation of LEF-1)
44297 Lovastatin increases_expression of Wnt-related gene
44305 CTNNB1 affects_activity of Lovastatin concerning neuroprotective function
44306 TCF3 affects_activity of Lovastatin concerning neuroprotective function
44737 Lovastatin decreases_activity of GSK3B
44743 Lovastatin affects_expression of CTNNB1 by inhibiting the phosphorylated GSK3B activity
44751 Lovastatin increases_activity of canonical Wnt signaling pathway to reduce the effect of Abeta (42)
44775 Lovastatin decreases_activity of HMGCR blocking thereby cholesterol biosynthesis
45039 Lovastatin increases_activity of CTNNB1 by inhibiting the phosphorylated GSK3B activity
17234346 Alzheimer disease
Metabolic
4,407
44800 Lovastatin interacts (colocalizes) with HMGCR
44801 Lovastatin decreases_activity of HMGCR
23703578 Metabolic
4,443
44920 Lovastatin decreases_quantity of Cholesterol
9600988 Metabolic
4,998
49377 Lovastatin decreases_activity of ARG2 in OxLDL-stimulated human aortic endothelial cells (HAECs)
21130456 Cardiovascular disease
Atherosclerosis
5,226
50922 Lovastatin decreases_quantity of Arachidonic acid in vascular endothelial cells
50923 Lovastatin decreases_quantity of Ca2+ in vascular endothelial cells
50927 Lovastatin decreases_quantity of Prostaglandin I2 in vascular endothelial cells
50929 Lovastatin decreases_activity of PTGS1 in vascular endothelial cells
50930 Lovastatin decreases_activity of PLA2G4A in vascular endothelial cells
19135546 Cardiovascular disease
5,266
51338 Lovastatin increases_activity of canonical Wnt signaling pathway
24511465 Alzheimer disease
Metabolic
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