Search Results for "Iron" - 56 interactions found in 22 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
839
4985 Parkinson disease increases_quantity of Iron
7998774 Parkinson disease
1,418
9876 ferroxidase activity affects_quantity of Iron in extracellular space
20817278 Alzheimer disease
1,420
12090 APP NOT increases_quantity of Iron
20817278 Alzheimer disease
1,422
9877 Iron interacts (colocalizes) with amyloid beta deposits in the brain cortex of AD (Alzheimer's disease) patients
9889 Iron affects_activity of neurodegeneration
9893 Iron is localized in Heme
9894 Iron increases_activity of amyloidosis in cultured neural cells
9898 Iron interacts (colocalizes) with neurofibrillary tangles
19021541 Alzheimer disease
1,441
10318 Iron affects_activity of striatal neuron in the substantia nigra (SN); of Parkinson's disease patients
10350 Iron is localized in basal ganglion in AD patients
10351 Iron is localized in ferritin-rich cell in AD patients
10384 Iron increases_activity of Alpha-secretase
19166904 Alzheimer disease
Hemochromatosis, type 1
1,505
10642 Iron increases_quantity of Reactive oxygen species
10646 Iron is localized in substantia nigra
20890618 Parkinson disease
1,506
10644 Iron affects_activity of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine in dopaminergic neurons
10645 Iron affects_activity of neuron projection development in dopaminergic neurons
20890618 Parkinson disease
1,511
10877 Amyloid beta peptide (42) interacts (colocalizes) with Fe3+
16205720 Alzheimer disease
1,538
10975 Iron increases_activity of mitochondrial depolarization by decreasing the mitochondrial membrane potential
10977 Iron increases_activity of neuron death by decreasing the mitochondrial membrane potential
10978 Ginsenoside Rg1 decreases_activity of neuron death if neuron death has been induced by iron
10979 Ginsenoside Rg1 decreases_activity of Iron by decreasing iron-induced mitochondrial membrane depolarisation
10980 6-OHDA increases_quantity of Iron by increasing iron influx
10981 Ginsenoside Rg1 decreases_quantity of Iron by decreasing 6-OHDA-induced iron influx
10982 6-OHDA increases_expression of SLC11A2
10983 Ginsenoside Rg1 decreases_expression of SLC11A2 if expression has been induced by 6-OHDA
10984 SLC11A2 increases_quantity of Iron by increasing the import of iron
10985 SLC11A2 increases_transport of Iron by increasing the import of iron
10986 6-OHDA increases_expression of ACO1
10987 6-OHDA increases_expression of IREB2
10988 Ginsenoside Rg1 decreases_quantity of ACO1
10989 Ginsenoside Rg1 decreases_quantity of IREB2
10990 6-OHDA increases_quantity of ACO1
10991 6-OHDA increases_quantity of IREB2
10992 ACO1 affects_activity of SLC11A2
10993 IREB2 affects_activity of SLC11A2
11109 Ginsenoside Rg1 affects_activity of iron ion homeostasis by decreasing 6-OHDA-induced iron influx
20872781 Parkinson disease
1,539
10997 Parkinson disease increases_quantity of Iron in substantia nigra
20872781 Parkinson disease
1,554
11093 Iron affects_quantity of HAMP
19898775 Alzheimer disease
1,709
12856 SOD1-p.G37R increases_quantity of Iron at the age of 12 months
19158288 Amyotrophic lateral sclerosis
2,035
16173 Iron is localized in arteriole in CAA
21187585 Alzheimer disease
3,311
30445 Fe3+ affects_folding of Amyloid beta peptide
21216965 Alzheimer disease
3,388
31684 Iron affects_activity of carnitine biosynthetic process
22134503 Diabetes mellitus, type II
Carnitine deficiency, systemic primary
Insulin resistance
Status epilepticus
Cardiovascular disease
3,792
37471 Iron increases_quantity of Advanced glycation end-product
37642 Fe2+ increases_quantity of Amyloid beta peptide (oligomer) The formation of covalently crosslinked high molecular weight Abeta oligomers is accelerated
37643 Fe3+ increases_quantity of Amyloid beta peptide (oligomer) The formation of covalently crosslinked high molecular weight Abeta oligomers is accelerated
19464758 Alzheimer disease
3,892
39435 Iron affects_activity of carnitine biosynthetic process
23150726 Diabetes mellitus, type II
Insulin resistance
4,140
42724 Iron decreases_expression of HIF1A in pancreas, in pancreatic beta cells
42725 Iron decreases_expression of HNF4A in pancreas, in pancreatic beta cells
42726 Iron decreases_expression of SLC2A1 in pancreas, in pancreatic beta cells
42727 Iron decreases_expression of SLC2A2 in pancreas, in pancreatic beta cells
42728 Iron decreases_activity of insulin secretion involved in cellular response to glucose stimulus in pancreas, in pancreatic beta cells
20440072 Diabetes mellitus, type II
Insulin resistance
4,284
43955 Iron decreases_activity of Restless legs syndrome
23905195 Restless legs syndrome
5,910
55825 HFE affects transport of Iron
55838 phagocytosis increases_quantity of Iron in reticuloendothelial macrophages; via phagocytosis of iron-loaded senescent red blood cells
Diabetes mellitus, type II
Insulin resistance
Hemochromatosis, type 1
6,649
64334 FXN affects_quantity of Iron in mitochondria
11175786 Diabetes mellitus, type II
Friedreich ataxia 1
Insulin resistance
6,664
64407 Iron NOT affects_expression of FXN
11986241 Friedreich ataxia 1
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