General Information:

Id: 990
Diseases: Alzheimer disease - [OMIM]
Mus musculus
TgCRND8 mouse
article
Reference: Chauhan NB and Sandoval J(2007) Amelioration of early cognitive deficits by aged garlic extract in Alzheimers transgenic mice Phytother Res 21: 629-640 [PMID: 17380553]

Interaction Information:

Comment TgCRND8 models show accelerated plaque development with a predominance of Abeta 42.
Formal Description
Interaction-ID: 6146

organism model

TgCRND8 mouse

increases_quantity of

Comment TgCRND8 models show accelerated plaque development with a predominance of Abeta 42.
Formal Description
Interaction-ID: 6147

organism model

TgCRND8 mouse

affects_quantity of

Comment Ageing increases the number of AD patients.
Formal Description
Interaction-ID: 6148

process

aging

increases_activity of

Comment Aged garlic extract can prevent progressive genesis of Abeta and cognitive decline in AD.
Formal Description
Interaction-ID: 6155

environment

Allium sativum (garlic) supplementation

decreases_quantity of

gene/protein

Amyloid beta peptide

Comment Aged garlic extract can prevent progressive genesis of Abeta and cognitive decline in AD.
Formal Description
Interaction-ID: 6156

environment

Allium sativum (garlic) supplementation

decreases_activity of