General Information:

Id: 989 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000793 SH-SY5Y cell
Reference: Niso-Santano M et al.(2010) Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis Free Radic. Biol. Med. 48: 1370-1381 [PMID: 20202476]

Interaction Information:

Comment Paraquat is a well known complex I inhibitor releasing reactive oxygen species (ROS) and dopaminergic toxicants. It is widely used to model PD.
Formal Description
Interaction-ID: 6145

drug/chemical compound


increases_quantity of

drug/chemical compound

Reactive oxygen species