General Information:

Id: 987
Diseases: Parkinson disease
Mus musculus
article
Reference: Andres-Mateos E et al.(2007) DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc. Natl. Acad. Sci. U.S.A. 104 [PMID: 17766438]

Interaction Information:

Comment DJ-1 is an atypical peroxiredoxin-like peroxidase that scavenges H2O2 through oxidation of Cys-106. In vivo there is an increase of DJ-1 oxidized at Cys-106 after MPTP intoxication of WT mice.
Formal Description
Interaction-ID: 6141

gene/protein

PARK7

decreases_quantity of

drug/chemical compound

H2O2

through oxidation of Cys-106
Drugbank entries Show/Hide entries for PARK7