General Information:

Id: 986 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0002104 BE(2)M17 cell
article
Reference: Canet-Aviles RM et al.(2004) The Parkinsons disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl. Acad. Sci. U.S.A. 101: 9103-9108 [PMID: 15181200]

Interaction Information:

Comment WT DJ-1 showed little specific localization to mitochondria. However, treatment with PQ2+ induced a localization of DJ-1 to mitochondrial outer membrane. Endogenous DJ-1 redistributed to mitochondria under oxidative conditions.
Formal Description
Interaction-ID: 6111

gene/protein

PARK7

is localized in

cellular component

mitochondrial outer membrane

after Paraquat treatment or under oxidative stress conditions
Drugbank entries Show/Hide entries for PARK7