General Information:

Id: 984 (click here to show other Interactions for entry)
Diseases: Huntington disease - [OMIM]
Parkinson disease
Mus musculus
BTO:0004102 cerebral cortical neuron (containing 20-30% astrocytes)
article
Reference: Johnson JA et al.(2008) The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration Ann. N. Y. Acad. Sci. 1147: 61-69 [PMID: 19076431]

Interaction Information:

Comment Replacing Nrf2 in astrocytes protects neurons against hydrogen peroxide.
Formal Description
Interaction-ID: 6104

drug/chemical compound

H2O2

increases_activity of

process

neuron death