General Information:

Id: 964 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Reference: Frojdo S et al.(2009) Alterations of insulin signaling in type 2 diabetes: a review of the current evidence from humans Biochim. Biophys. Acta 2: 83-92 [PMID: 19041393]

Interaction Information:

Comment While PKB-alpha is involved in the regulation of lipid metabolism, the activation of glycogen synthesis in skeletal muscle, and in insulin action in adipose cells, it is PKB-beta (the major isoform expressed in skeletal muscle) that is considered to be the key isoform involved in insulin metabolic actions.
Formal Description
Interaction-ID: 6249



affects_activity of

in adipose tissue
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