General Information:
Id: | 952 (click here to show other Interactions for entry) |
Diseases: |
Alzheimer disease
- [OMIM]
|
Mammalia | |
review | |
Reference: | Han W and Li C(2010) Linking type 2 diabetes and Alzheimers disease Proc. Natl. Acad. Sci. U.S.A. 107: 6557-6558 [PMID: 20385830] |
Interaction Information:
Comment | Insulin and leptin regulate Abeta levels by modulating Abeta production via their actions on BACE and/or gamma-secretase, as well as by modulating Abeta degradation via Abeta-degrading enzymes, such as insulin-degrading enzyme. |
Formal Description Interaction-ID: 5828 |
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