CIDeRGeneral Information:
| Id: | 952 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
|
| Mammalia | |
| review | |
| Reference: | Han W and Li C(2010) Linking type 2 diabetes and Alzheimers disease Proc. Natl. Acad. Sci. U.S.A. 107: 6557-6558 [PMID: 20385830] |
Interaction Information:
| Comment | Insulin and leptin regulate Abeta levels by modulating Abeta production via their actions on BACE and/or gamma-secretase, as well as by modulating Abeta degradation via Abeta-degrading enzymes, such as insulin-degrading enzyme. |
|
Formal Description Interaction-ID: 5828 |
|