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Diseases	Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	952 (click here to show other Interactions for entry)
Diseases:	Alzheimer disease - [OMIM]
Organism:	Mammalia
Publication type:	review
Reference:	Han W and Li C(2010) Linking type 2 diabetes and Alzheimers disease Proc. Natl. Acad. Sci. U.S.A. 107: 6557-6558 [PMID: 20385830]

Interaction Information:

Comment	Insulin and leptin regulate Abeta levels by modulating Abeta production via their actions on BACE and/or gamma-secretase, as well as by modulating Abeta degradation via Abeta-degrading enzymes, such as insulin-degrading enzyme.
Formal Description Interaction-ID: 5828	gene/protein LEP affects_quantity of gene/protein Amyloid beta peptide

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