General Information:

Id: 924 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
Tg2576 mouse model
primary neurons
article
Reference: Rezai-Zadeh K et al.(2005) Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice J. Neurosci. 25: 8807-8814 [PMID: 16177050]

Interaction Information:

Comment Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid beta peptide generation and reduces cerebral amyloidosis in Alzheimer transgenic mice.
Formal Description
Interaction-ID: 5595

drug/chemical compound

Epigallocatechin 3-gallate

decreases_quantity of

gene/protein

Amyloid beta peptide

in primary neurons; derived from Swedish mutant APP-overexpressing mice TgAPPswl line 2576