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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	918 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Mus musculus
Publication type:	article
Reference:	Liu Y et al.(2008) A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature 456: 269-273 [PMID: 18849969]

Interaction Information:

Comment	The reciprocal upregulation of FOXO1 activity by SIRT1 during prolonged fasting seems to be critical in maintaining energy balance through its effects on glucose metabolism.
Formal Description Interaction-ID: 5671	gene/protein FOXO1 affects_activity of process glucose metabolic process

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