General Information:

Id: 918 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
Reference: Liu Y et al.(2008) A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature 456: 269-273 [PMID: 18849969]

Interaction Information:

Comment The reciprocal upregulation of FOXO1 activity by SIRT1 during prolonged fasting seems to be critical in maintaining energy balance through its effects on glucose metabolism.
Formal Description
Interaction-ID: 5671



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