General Information:

Id: 908 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Atherosclerosis
Parkinson disease
Mammalia
review
Reference: Sun AY et al.(2008) Botanical phenolics and brain health Neuromolecular Med. 10: 259-274 [PMID: 19191039]

Interaction Information:

Comment Abeta-mediated ROS production is also linked to increased inflammatory responses, including increased production of cytokines, nitric oxide and eicosanoids.
Formal Description
Interaction-ID: 5423

drug/chemical compound

Reactive oxygen species

increases_activity of

in astrocytes; if ROS production is Abeta-induced
Comment Resveratrol is found in a variety of plant species and is used to treat fevers, hyperlipidemia, atherosclerosis, and inflammation.
Formal Description
Interaction-ID: 5514

drug/chemical compound

Resveratrol

decreases_activity of

Drugbank entries Show/Hide entries for Resveratrol
Comment Curcumin offers antioxidant, anti-inflammatory and cholesterol lowering properties, all are important on ameliorating the deleterious consequences of AD.
Formal Description
Interaction-ID: 5551

drug/chemical compound

Curcumin

decreases_activity of