General Information:

Id: 908 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Atherosclerosis
Parkinson disease
Mammalia
review
Reference: Sun AY et al.(2008) Botanical phenolics and brain health Neuromolecular Med. 10: 259-274 [PMID: 19191039]

Interaction Information:

Comment Neuroprotective effects of resveratrol are known.
Formal Description
Interaction-ID: 5512

drug/chemical compound

Resveratrol

increases_activity of

process

neuroprotection

Drugbank entries Show/Hide entries for Resveratrol
Comment Resveratrol is found in a variety of plant species and is used to treat fevers, hyperlipidemia, atherosclerosis, and inflammation.
Formal Description
Interaction-ID: 5514

drug/chemical compound

Resveratrol

decreases_activity of

Drugbank entries Show/Hide entries for Resveratrol
Comment Resveratrol is found in a variety of plant species and is used to treat fevers, hyperlipidemia, atherosclerosis, and inflammation.
Formal Description
Interaction-ID: 5515

drug/chemical compound

Resveratrol

decreases_activity of

phenotype

hyperlipidemia

Drugbank entries Show/Hide entries for Resveratrol
Comment Resveratrol is found in a variety of plant species and is used to treat fevers, hyperlipidemia, atherosclerosis, and inflammation.
Formal Description
Interaction-ID: 5516

drug/chemical compound

Resveratrol

decreases_activity of

Drugbank entries Show/Hide entries for Resveratrol
Comment Resveratrol is found in a variety of plant species and is used to treat fevers, hyperlipidemia, atherosclerosis, and inflammation.
Formal Description
Interaction-ID: 5517

drug/chemical compound

Resveratrol

decreases_activity of

Drugbank entries Show/Hide entries for Resveratrol
Comment Several studies demonstrated the ability for resveratrol to protect neurons against Abeta induced toxicity.
Formal Description
Interaction-ID: 5519

drug/chemical compound

Resveratrol

decreases_quantity of

Drugbank entries Show/Hide entries for Resveratrol
Comment Reveratrol is able to reduce Abeta secretion in several cell lines via a mechanism that involves the proteasome.
Formal Description
Interaction-ID: 5528

drug/chemical compound

Resveratrol

decreases_quantity of

gene/protein

Amyloid beta peptide

via a mechanism that involves the proteasome
Drugbank entries Show/Hide entries for Resveratrol
Comment A number of studies have demonstrated the ability of resveratrol to suppress neuroinflammatory responses, e.g., attenuating iNOS and COX-2 expression.
Formal Description
Interaction-ID: 5531

drug/chemical compound

Resveratrol

decreases_expression of

gene/protein

PTGS2

Drugbank entries Show/Hide entries for Resveratrol or PTGS2
Comment A number of studies have demonstrated the ability of resveratrol to suppress neuroinflammatory responses, e.g., attenuating iNOS and COX-2 expression.
Formal Description
Interaction-ID: 5536

drug/chemical compound

Resveratrol

decreases_expression of

gene/protein

NOS2

Drugbank entries Show/Hide entries for Resveratrol or NOS2
Comment Effects of common botanicals on Alzheimer disease.
Formal Description
Interaction-ID: 5744

drug/chemical compound

Resveratrol

affects_activity of

in Tg2576 mouse
Drugbank entries Show/Hide entries for Resveratrol