General Information:

Id: 904 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Mus musculus
BAC-based transgenic Sirt1 mouse with moderate overexpression of Sirt1
article
Reference: Pfluger PT et al.(2008) Sirt1 protects against high-fat diet-induced metabolic damage. Proc. Natl. Acad. Sci. U.S.A. 105: 9793-9798 [PMID: 18599449]

Interaction Information:

Comment Transgenic Sirt1 mice exhibited increased food intake compared with wild-type mice on high-fat diet.
Formal Description
Interaction-ID: 5375

gene/protein

SIRT1

affects_activity of

on high-fat diet, if SIRT1 is overexpressed