General Information:

Id: 897 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article
Reference: Milne JC et al.(2007) Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 450: 712-716 [PMID: 18046409]

Interaction Information:

Comment As observed in calorie restriction, SRT1720 treatment (10 weeks) increases mitochondrial capacity by 15% in gastrocnemius muscle as measured by citrate synthase activity.
Formal Description
Interaction-ID: 5318

gene/protein

SIRT1

increases_activity of

gene/protein

CS

in gastrocnemius muscle
Drugbank entries Show/Hide entries for CS