General Information:

Id: 886 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Hara K et al.(2002) A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes Diabetologia 45: 740-743 [PMID: 12107756]

Interaction Information:

Comment Taken together with the reported data showing that plasma fasting insulin is linked to chromosome 4p15.1, where the PGC-1 gene is located, the results of the study suggest that the PGC-1 gene is implicated in the pathogenesis of Type II diabetes.
Formal Description
Interaction-ID: 5234

gene/protein

PPARGC1A

affects_activity of