General Information:

Id: 866 (click here to show other Interactions for entry)
Diseases: Cancer
Parkinson disease
Mus musculus
BTO:0000944 NIH-3T3 cell
article
Reference: Kim YC et al.(2009) Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN. Int. J. Oncol. 35: 1331-1341 [PMID: 19885556]

Interaction Information:

Comment Both wild-type and C106S-DJ-1 mutant directly bound to PTEN and inhibited PTEN phosphatase activity. C106S-DJ-1 inhibited the activity more strongly than wt-DJ-1.
Formal Description
Interaction-ID: 17846

gene/protein

PARK7

decreases_activity of

gene/protein

PTEN

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